I am about to marry my cousin.what is the chance of homozygosity in the offsprings?

Question

'cousin' as i mentioned above is related to me as my mother's sister's daughter.she is same age as mine.phenotypically very similar complexion.what is the chance of homozygosity in this cross?

Answer 1

You want inbred knuckle-draggers with three eyes; go for it pal!

Answer 2

There is somewhat greater incidence of birth defects (4-6%) in the marriages between the first cousins, relative to that in the general population of about 3-4%. This is not a very significant increase per se, however -- unless there are inherited genetic deseases in the family.

Answer 3

Sounds like you are having trouble with biology homework. At least that's what I'd like to think, because marrying your cousin? I think there might be other things you have to worry about than homozygosity.

Answer 4

There are millions of women in the world. I strongly suggest you NOT marry your cousin. Look outside of your family for a wife. The risks to offspring of inbreeding, not to mention the social stigma is not worth it.

Answer 5

Contrary to widely held beliefs and longstanding taboos in America,
first cousins can have children together without a great risk of
birth defects or genetic disease, scientists are reporting today.
They say there is no biological reasonto discourage cousins from marrying.
First cousins are somewhat more likely than unrelated parents to
have a child with a serious birth defect, mental retardation or
genetic disease, but their increased risk is nowhere near as large
as most people think, the scientists said.

In the general population, the risk that a child will be born with a
serious problem like spina bifida or cystic fibrosis is 3 percent to
4 percent; to that background risk, first cousins must add another
1.7 to 2.8 percentage points, the report said.

Although the increase represents a near doubling of the risk, the
result is still not considered large enough to discourage cousins
from having children, said Dr. Arno Motulsky, a professor emeritus
of medicine and genome sciences at the University of Washington,
and the senior author of the report.

"In terms of general risks in life it's not very high,"
Dr. Motulsky said. Even at its worst, 7 percent, he said,
"93 percent of the time, nothing is going to happen."

The report is in today's issue of The Journal of Genetic Counseling.

"As genetic advisers," Dr. Motulsky said, "we give people all the
various possibilities and risks and leave it up to them to make a
decision. Some might decide a doubling of the risk is not
something they want to face.

He and his colleagues said no one questioned the right of people
with genetic disorders to have children, even though some have far
higher levels of risk than first cousins. For example, people with
Huntington's disease, a severe neurological disorder that comes on
in adulthood, have a 50 percent chance of passing the
disease to their children.


good luck. the link below has more info if you are still unsure.

Answer 6

These kinds of marriages are very common in Pakistan and other backward countries. It causes the population in general to be stupid and ineducable. It causes a serious inbreeding problem DO NOT HAVE KIDS. Please. It is expensive for society to treat these offspring. It is incest and wrong.

Answer 7

You CANT marry you cousin Under U.S. law. unless ur marrying in a different country then the chances of ur children lookin real funky are pretty good.

Answer 8

Wow. You should really re-think this or decide now not to have kids. I would not take the chance on having deformed children.

Answer 9

Dude

Answer 10

I would say that yes there is a fairly large chance....I would try seeing a doctor...to tell you the chances of that

Answer 11

See a genetisies