why does pernicious anemia occurs when there is lack of intrinsic factor in the body.or maybe what is the relationship between intrinsic factor and pernicious anemia.
2007-04-17 23:48:40 · 2 answers · asked by samiyot 1 in Health ➔ Other - Health
the intrinsic factor is mainly present in the stomach and it's role is to unit with vitamin B12(extrinsic factor)to prevent its digestion by stomach enzymes.to form a complex which passes to the small intestin where they leave each other and the vit B 12 is being absorbed by the small intestin.
if there is a lack in intrinsic factor there will be no absorption to vit.B12 which is essantial for formation of RBC'S and their maturation leading to vit b12 deficiency anemia=pernicious anemia
2007-04-18 00:02:25 · answer #1 · answered by Pinka 3 · 1⤊ 0⤋
in tr. factor enables absorption of B12 vitamin,
if is produced in stomach,
Schilling's test :parenteral given B12 improves anemia
2007-04-18 06:59:03 · answer #2 · answered by Srbo Sutaric 5 · 0⤊ 0⤋