Why is total perinteral nutrition hard on the liver?

Question

I have read several medical blogs about children with various medical conditions that are TPN-dependent. I know of at least one child who went into liver failure as a result of this. What causes this form of nutrition to be so hard on the liver?

Answer 1

This is because it is very concentrated and there is just so much that the liver can metabolise at a time. If it continues then the liver gets damaged and if it continues further then one can go into liver failure. This is why liver functions are kept under a check all the time that one is getting TPN, good luck