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Hi, i am on Nifedipine 20 mg twice a day on morning and evening for my high blood pressure. Nifedipine is a belong a to group of high blood pressure medication calcium blocker, on a long term usage will it has any serious side effect on the body and will it effect my bone density on long run? thanks

2007-04-15 16:34:35 · 10 answers · asked by allen s 2 in Health Diseases & Conditions Other - Diseases

10 answers

Nifedipine is generic for Adalat or Procardia or Procardia XL

What should I avoid while taking nifedipine?

Do not consume grapefruit or grapefruit juice during treatment with nifedipine. Nifedipine can interact with grapefruit and grapefruit juice, and the interaction may have dangerous effects. You should discuss the use of grapefruit and grapefruit juice with your doctor.

Follow any recommendations your doctor makes about diet or exercise.

Use caution when you stand or sit up from a lying position, especially if you wake up during the night. You may become dizzy when changing positions.
Use alcohol cautiously. Alcohol may further lower blood pressure and increase drowsiness or dizziness while taking nifedipine.

What are the possible side effects of nifedipine?

If you experience any of the following serious side effects, stop taking nifedipine and contact your doctor immediately or seek emergency medical treatment:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
unusually fast or slow heartbeats;
severe dizziness or fainting;
psychosis;
yellowing of the skin or eyes (jaundice); or
swelling of the legs or ankles.


Other, less serious side effects may be more likely to occur. Continue to take nifedipine and talk to your doctor if you experience

headache, fatigue, or tiredness;
flushing;
insomnia;
vivid or abnormal dreams;
nausea or constipation; or
increased urination.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.


What other drugs will affect nifedipine?

Before taking nifedipine, tell your doctor if you are taking any of the following drugs:

another heart medication to treat the same or another condition;
cimetidine (Tagamet, Tagamet HB);
erythromycin (E-Mycin, E.E.S., Eryc, Ery-Tab, others);
itraconazole (Sporanox) or ketoconazole (Nizoral);
carbamazepine (Tegretol);
phenytoin (Dilantin); or
rifampin (Rifadin, Rimactane) or rifabutin (Mycobutin).
You may not be able to take nifedipine, or you may require a dosage adjustment or special monitoring if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with nifedipine or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.


Now, here comes the numerous controversies. A lot of articles stated that pts on CCB (calcium channel blockers) such as Nifepidine(Procardia) , Verpamil,(Calan) Diltiazem (Cardizem) shouldn't be taking calcium supplements. Calcium supplements ( may contain lead) may also decrease the efficacy of calcium channel . However, other studies suggested that Inadequate calcium intake may contribute to accelerated bone loss and density. .There is an ongoing debate whether these calcium channel blockers increase the risks of heart attacks.; as these meds block the transport of calcium across the muscle cell membrane.


Calcium. Calcium regulates the tone of the smooth muscles lining blood vessels, and population studies have found that people who have sufficient dietary calcium have lower blood pressure than those who do not. Hypertension itself increases calcium loss from the body. The effects of extra calcium on blood pressure, however, are mixed with some even showing higher pressure.


Effects of Anti-Hypertensive Drugs on Exercise. Certain anti-hypertensive medications, including diuretics and beta-blockers, can interfere with exercise capacity. ACE inhibitors or calcium-channel blockers are the best drugs for active individuals. However, patients who must take drugs that interfere somewhat with exercise capability should still adhere to an exercise program and consult a physician on how best to balance medications with exercise.


Dash Diet (Dietary Approaches to Stop Hypertension) is rcommended for Hypertensive pts. It's low salt to avoid more potassium loss. It's rich in fruits and vegetables. and nutrients and calcium obtained from foods naturally. They also contain other nutirents such as potassium and magnesium which help in the absorption of Ca.


The site below also mentioned no bone loss:


Times Leader | 01/23/2007 | Blood pressure medicine will not cause bone ...
Blood pressure medicine will not cause bone loss Ask Dr. H ... Norvasc is in the class of blood pressure medications called "calcium channel blockers. ...www.timesleader.com/mld/timesleader/living/16523308

2007-04-15 17:06:11 · answer #1 · answered by rosieC 7 · 0 0

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2016-05-20 02:32:36 · answer #2 · answered by ? 3 · 0 0

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2016-09-17 09:27:16 · answer #3 · answered by ? 3 · 0 0

3 years ago, I was diagnosed - hypertension with a reading of 160/100. I used to feel dizzy a lot, my legs had awful cramps, and levels were very low in my potassium, causing my fingers and toes to always cramp together. One day I started to feel really faint while I was driving with my daughter in the back seat and I passed out, hitting 3 cars and ending up in a ditch. That moment,I knew I had to do something because my meds weren't working. I heard about this diet from a friend and thought I'd give it a shot. The results have been remarkable. In just 21 days, I honestly can't remember feeling this good, my blood pressure went from 175/110 to 125/70.

2016-05-18 02:24:52 · answer #4 · answered by Anonymous · 0 0

Nifedipine Side Effects

2016-09-29 21:56:55 · answer #5 · answered by ? 4 · 0 0

I found a great link for you on long term uses of Captopril (Nifedipine), and I am a nurse, and I have seen patients on this for the rest of their of life, no bad side effects become of it. As far as bone density, you will just need to take a multi-vitamin that has calcium in it just to keep your calcium level up. I hope this article helps and good luck.

2007-04-15 17:00:37 · answer #6 · answered by dwynallison 1 · 0 0

Possible Side Effects of Drugs That Lower Blood Pressure Some of the drugs listed below can affect certain functions of the body, resulting in bad side effects. However, drugs that lower blood pressure have proven effective over the years. The benefits of using them far outweigh the risk of side effects. Most people who’ve taken these drugs haven’t had any problems. Diuretics — Some of these drugs may decrease your body's supply of a mineral called potassium. Symptoms such as weakness, leg cramps or being tired may result. Eating foods containing potassium may help prevent significant potassium loss. You can prevent potassium loss by taking a liquid or tablet that has potassium along with the diuretic, if your doctor recommends it. Diuretics such as amiloride (Midamar), spironolactone (Aldactone) or triamterene (Dyrenium) are called "potassium sparing" agents. They don’t cause the body to lose potassium. They might be prescribed alone but are usually used with another diuretic. Some of these combinations are Aldactazide, Dyazide, Maxzide or Moduretic. Some people suffer from attacks of gout after prolonged treatment with diuretics. This side effect isn't common and can be managed by other treatment. In people with diabetes, diuretic drugs may increase the blood sugar level. A change in drug, diet, insulin or oral antidiabetic dosage corrects this in most cases. Your doctor can change your treatment. Most of the time the degree of increase in blood sugar isn't much. Impotence may also occur in a small percentage of people. Beta-blockers — Acebutolol (Sectral), atenolol (Tenormin), metoprolol (Lopressor), nadolol (Corgard), pindolol (Visken), propranolol (Inderal) or timolol (Blocadren) may cause insomnia, cold hands and feet, tiredness or depression, a slow heartbeat or symptoms of asthma. Impotence may occur. If you have diabetes and you’re taking insulin, have your responses to therapy monitored closely. ACE inhibitors — These drugs, such as captopril (Capoten), enalapril (Vasotec), lisinopril (Zestril or Prinivil), may cause a skin rash; loss of taste; a chronic dry, hacking cough; and in rare instances, kidney damage. Angiotensin II receptor blockers — These drugs may cause occasional dizziness. Calcium channel blockers — Diltiazem (Cardizem), nicardipine (Cardene), Nifedipine (Procardia) and verapamil (Calan or Isoptin) may cause palpitations, swollen ankles, constipation, headache or dizziness. Side effects with each of these drugs differ a great deal. Alpha blockers — These drugs may cause fast heart rate, dizziness or a drop in blood pressure when you stand up. Combined alpha and beta blockers — People taking these drugs may experience a drop in blood pressure when they stand up. Central agonists — Alpha methyldopa (Aldomet) may produce a greater drop in blood pressure when you're in an upright position (standing or walking) and may make you feel weak or faint if the pressure has been lowered too far. This drug may also cause drowsiness or sluggishness, dryness of the mouth, fever or anemia. Male patients may experience impotence. If this side effect persists, your doctor may have to change the drug dosage or use another medication. Clonidine (Catapres), guanabenz (Wytensin) or guanfacine (Tenex) may produce severe dryness of the mouth, constipation or drowsiness. If you're taking any of these drugs, don’t stop suddenly, because your blood pressure may rise quickly to dangerously high levels. Peripheral adrenergic inhibitors — Reserpine may cause a stuffy nose, diarrhea or heartburn. These effects aren't severe and no treatment is required other than to change the amount of drugs taken. If you have nightmares or insomnia or get depressed, tell your doctor. You should stop using the drugs. Guanadrel (Hylorel) or guanethidine (Ismelin) may cause some diarrhea, which may persist in some people. This side effect usually becomes less of a problem if you continue treatment. These drugs reduce blood pressure more when you stand. Consequently, you may get dizzy and lightheaded and feel weak when you get out of bed in the morning or stand up suddenly. If you notice any of these reactions — and if they persist for more than a minute or two — sit or lie down and either reduce or omit the next dose of the drug. If symptoms continue, contact your doctor. When you're taking guanethidine, don't keep standing in the hot sun or at a social gathering if you begin to feel faint or weak. These activities cause low blood pressure. Male patients may experience impotence. Contact your doctor if this occurs. These drugs are rarely used unless other medications don’t help. Blood vessel dilators — Hydralzine (Apresoline) may cause headaches, swelling around the eyes, heart palpitations or aches and pains in the joints. Usually none of these symptoms are severe, and most will go away after a few weeks of treatment. This drug isn't usually used by itself. Minoxidil (Loniten) is a potent drug that's usually used only in resistant cases of severe high blood pressure. It may cause fluid retention (marked weight gain) or excessive hair growth.

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2016-04-13 22:39:55 · answer #7 · answered by Anonymous · 0 0

Hey guys, The best progress that I have ever had was with Rays perfect remedy (just google it) Without a doubt the most incredible results that I have ever had for diabetes.

2016-08-09 23:06:55 · answer #8 · answered by Raouf Zeroual 2 · 0 0

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2017-02-24 03:28:58 · answer #9 · answered by ? 3 · 0 0

like both, fruits: berries, oatmeal, pears, peaches, dragonfruit, pomegranate.... Vegetables: CUCUMBERS, bok choy, green beans, broccoli,.... We guess the two are great.

2017-02-17 04:50:02 · answer #10 · answered by ? 3 · 0 0

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