What is reticulocyte crisis?

Question

Also what is its cause? Pls help!!

Answer 1

Reticulocyte crisis is when immature RBCs are released into the blood before they have fully-developed, and is most commonly seen in blood disorders where the circulating RBCs are being destroyed at a very rapid rate. These are typically seen when RBC morphology is abnormal and they become destroyed by the spleen -- e.g. sickle-cell, spherocytosis, etc

Answer 2

Reticulocytes are immature Red Blood Cells. RBCs are not normally released by the marrow until they are mature, but in situations where mature calls are lost at an abnormal rate, or there is an abnormality in the marrow, they are relaesed early.
Causes of mature RBC loss include hemoglobinopathies (sickle cell, C disease), thalassemia, hemorrhage, abnormal menses. Marrow pathologies include polycythemia rubra vera, medications, hypervitiminosis. As you can see, the cause must be investigated further.

Answer 3

All people with hemolytic anemias rely on high erythrocyte production rates to maintain adequate hemoglobin levels. Examples include sickle cell disease, thalassemia intermedia, and severe pyruvate kinase deficiency. If the capacity of the bone marrow to manufacture new red cells is compromised, the hematocrit can dramatically fall to levels that are potentially deadly.
This is reticulocyte crisis
http://www.scinfo.org/anemia.htm