What are some new pharmaceutical drugs on the market that are of natural origin? i.e. plants, microbial, etc?

Answer 1

A search of the medical literature combining:
1 exp Drug Design/
2 exp Plant Preparations/ or exp Drugs, Chinese Herbal/ or exp Medicine, Herbal/ or exp Plant Extracts/ or exp Plants, Medicinal/
found these articles:
Zhang YN. Zhong XG. Zheng ZP. Hu XD. Zuo JP. Hu LH. Discovery and synthesis of new immunosuppressive alkaloids from the stem of Fissistigma oldhamii (Hemsl.) Merr. Bioorganic & Medicinal Chemistry. 15(2):988-96, 2007 Jan 15.

Ball AR. Casadei G. Samosorn S. Bremner JB. Ausubel FM. Moy TI. Lewis K. Conjugating berberine to a multidrug efflux pump inhibitor creates an effective antimicrobial. ACS Chemical Biology 1(9):594-600, 2006 Oct 24.

Yu D. Morris-Natschke SL. Lee KH. New developments in natural products-based anti-AIDS research. Medicinal Research Reviews. 27(1):108-32, 2007 Jan.

Ott KH. Aranibar N. Nuclear magnetic resonance metabonomics: methods for drug discovery and development. Methods in Molecular Biology. 358:247-71, 2007.

Yang XX. Hu ZP. Duan W. Zhu YZ. Zhou SF. Drug-herb interactions: eliminating toxicity with hard drug design. Current Pharmaceutical Design. 12(35):4649-64, 2006.

Reddy KR. Kayastha AM. Boric acid and boronic acids inhibition of pigeonpea urease. Journal of Enzyme Inhibition & Medicinal Chemistry. 21(4):467-70, 2006 Aug.

Ahmad B. Khan H. Bashir S. Nisar M. Hassan M. Inhibition activities of Colchicum luteum baker on lipoxygenase and other enzymes. Journal of Enzyme Inhibition & Medicinal Chemistry. 21(4):449-52, 2006 Aug.

Wang Y. Wang X. Cheng Y. A computational approach to botanical drug design by modeling quantitative composition-activity relationship. Chemical Biology & Drug Design. 68(3):166-72, 2006 Sep.

Buenz EJ. Bauer BA. Johnson HE. Tavana G. Beekman EM. Frank KL. Howe CL. Searching historical herbal texts for potential new drugs. BMJ. 333(7582):1314-5, 2006 Dec 23.

Sastry BS. Suresh Babu K. Hari Babu T. Chandrasekhar S. Srinivas PV. Saxena AK. Madhusudana Rao J. Synthesis and biological activity of amide derivatives of nimbolide. Bioorganic & Medicinal Chemistry Letters. 16(16):4391-4, 2006 Aug 15.

Rollinger JM. Langer T. Stuppner H. Integrated in silico tools for exploiting the natural products' bioactivity. Planta Medica. 72(8):671-8, 2006 Jun.

Chua TK. Koh HL. Medicinal plants as potential sources of lead compounds with anti-platelet and anti-coagulant activities. Mini-Reviews in Medicinal Chemistry. 6(6):611-24, 2006 Jun.

Rollinger JM. Langer T. Stuppner H. Strategies for efficient lead structure discovery from natural products. Current Medicinal Chemistry. 13(13):1491-507, 2006.

Pedras MS. Jha M. Toward the control of Leptosphaeria maculans: design, syntheses, biological activity, and metabolism of potential detoxification inhibitors of the crucifer phytoalexin brassinin. Bioorganic & Medicinal Chemistry. 14(14):4958-79, 2006 Jul 15.

Nascimento MA. Silva AK. Franca LC. Quignard EL. Lopez JA. Almeida MG. Turnera ulmifolia L. (Turneraceae): preliminary study of its antioxidant activity. Bioresource Technology. 97(12):1387-91, 2006 Aug.

Yang XG. Zhang GH. Li W. Peng B. Liu ZD. Pan WS. Design and evaluation of jingzhiguanxin monolithic osmotic pump tablet. Chemical & Pharmaceutical Bulletin. 54(4):465-9, 2006 Apr.

Wang YH. Zhang HX. Li Q. Ding Y. Hu JJ. Du GH. [High-throughput screening assay for groups of effective components extracted from Xiaoxuming Recipe]. [Chinese] Zhong Xi Yi Jie He Xue Bao/Journal of Chinese Integrative Medicine. 4(1):64-7, 2006 Jan.

Pedras MS. Suchy M. Design, synthesis, and antifungal activity of inhibitors of brassilexin detoxification in the plant pathogenic fungus Leptosphaeria maculans. Bioorganic & Medicinal Chemistry. 14(3):714-23, 2006 Feb 1.

Mukherjee PK. Wahile A. Integrated approaches towards drug development from Ayurveda and other Indian system of medicines. Journal of Ethnopharmacology. 103(1):25-35, 2006 Jan 3.

Suresh Babu K. Hari Babu T. Srinivas PV. Hara Kishore K. Murthy US. Rao JM. Synthesis and biological evaluation of novel C (7) modified chrysin analogues as antibacterial agents. Bioorganic & Medicinal Chemistry Letters. 16(1):221-4, 2006 Jan 1.