sickle cell?

Question

if my dad had sickle cell and my mom didnt but i have the trait of it, is it likely that i will get it???.................. cuz im like almost always getting sick as if i have a weak immune systom.! goodness. I hope i dont have it :(

So was I born with the trait or born with the disease?

i meant to say my dad HAS and my mom doesnt have. Sorry bout the past tense. im 18 btw. :)

Answer 1

Sickle-cell disease is a general term for a group of genetic disorders caused by sickle hemoglobin (Hgb S or Hb S). In many forms of the disease, the red blood cells change shape, usually looking much like that of a banana, upon deoxygenation because of polymerization of the abnormal sickle hemoglobin. This process damages the red blood cell membrane, and can cause the cells to become stuck in blood vessels. This deprives the downstream tissues of oxygen and causes ischemia and infarction. The disease is chronic and lifelong. Individuals are most often well, but their lives are punctuated by periodic painful attacks. In addition to periodic pain, there may be damage of internal organs, such as stroke. Lifespan is often shortened with sufferers living to an average of 40 years. Sickle-cell disease occurs more commonly in people (or their descendants) from parts of the world such as sub-Saharan Africa, where malaria is or was common, but it also occurs in people of other ethnicities. The mutated gene is recessive, meaning it must be inherited from each parent for the individual to have the disease. When it is expressed the proteins inside the red blood cells stretch out and form into a sickle shape, preventing their passage through the capillaries.


Infections. Infants and young children with sickle cell disease are especially vulnerable to serious bacterial infections, such as those that cause meningitis (infection of the lining of the brain) and blood infection. Infections are a major cause of death in children with sickle cell disease. But deaths have declined dramatically since doctors began routinely treating children with sickle cell disease with the antibiotic penicillin to help prevent these infections. Affected children should receive penicillin twice daily between the ages of 2 months and at least 5 years of age.1,2 Most children with sickle cell disease are now identified through newborn screening tests, so they can receive special medical care to help prevent complications.

Answer 2

If you have the trait, you will not progress to the disease. Sickle cell is a genetic disease. It does not develop from the trait. If you are unsure of your status, get the simple blood test. If you are an adult, you should have had symptoms of the disease before now.


Sickle cell disease affects more than 72,000 Americans, primarily those of African heritage, but also those of Arabian, Asian, Caribbean, Indian, Mediterranean, and South and Central American descent.


Hemoglobin, which is found in all red blood cells, carries oxygen from the lungs to tissues and organs throughout the body.
Normal red blood cells are soft, smooth and round and can move easily through the body.
When affected by sickle cell disorders, the red blood cells become rigid, sticky and sickle-shaped and are more fragile. This results in periodic plugging of blood vessels, thereby preventing the delivery of oxygen to tissues and organs.


Sickle cell trait is a condition in which there is one gene for the formation of sickle hemoglobin and one for the formation of normal hemoglobin. Sickle cell trait occurs in one out of every 10 African Americans. Usually, people with sickle cell trait do not have any medical problems and they can lead normal lives. They do not develop sickle cell disease.

You can only know if you have the trait or disease by having a simple blood test.

Sickle cell disease is inherited in a recessive manner.
If you have the trait, you might want to keep that in mind if you decide to have children. You may want to consider having genetic counseling.
If you have the trait and your partner is normal, you have a 50-50% chance of having a normal child or one with a trait.
If your partner would have the trait as well, you would have a 25% chance of having a child with sickle cell disease, 50% chance of having a child with the trait and 25% chance of having an unaffected child.
If your partner had the disease, you would have a 50% chance of having a child with the disease or a 50% chance of having a child with the trait. If you truly have the disease and not the trait, these figures would be different.

The trait has no connection with a weak immune system. If you are having problems getting sick all the time, get checked by a dr. There are other things from diabetes to infections that could be affecting your immune system.

Answer 3

If your father had sickle cell disease and your mom did not, you will have the trait. If your dad had the trait and your mom did not, then you have a 50% chance of also carrying the trait.
Sickel cell is not part of your immune system. Sickle cell disease and trait get sick for other reasons, but their immune system usually works fine. It would best to ask your parents, if they are unavailable, simple blood tests can be performed to identify abnormal red blood cells, like sickle cells.

Sickle cell trait is a condition in which there is one gene for the formation of sickle hemoglobin and one for the formation of normal hemoglobin. Sickle cell trait occurs in one out of every 10 African Americans. Usually, people with sickle cell trait do not have any medical problems and they can lead normal lives. They do not develop sickle cell disease.

Answer 4

Sickle cell is a recessive disease, so you have to have two copies of the gene, which your father has, and passed one on to you. Unless your mother is a carrier (has one normal and one sickle cell gene) then you are only a carrier and will not get the disease. Good news is if that is the case then you are resistant to malaria.

Answer 5

How old are you? Most likely born with the trait.. which means you need to talk to you OBGYN before trying to have a baby. You will probably need to have tests run through an infectious desiese specialist and they will tell you what your percentage will be for your children being born with either the trait or the desiese. Hope this helps!

Answer 6

you are a carrier of the disease. this means that you don't have symptoms, but you carry the disease in your genes. if you have children with a guy who doesn't have it or who isn't a carrier, then statistically, half your children will be carriers and the other half clean. if your kids' father is a carrier, then half your kids will have it and half your kids won't. if your guy has it, then half your kids will have it and half will be carriers. so in short, you were born with one gene for sickle cell and one for normal blood, so you are just a carrier, and do not experience symptoms.