Could the harnessing of energy from the nucleus been achieved without Einstein's insight that E=MC2?

Question

Were there any other practical applications resulting from the many facets of his theories of relativity?

Answer 1

It pretty much was.

E = mc2 arises from a classical theory. Splitting the atom requires a quantum theory.

Einstein had nothing at all to do with nuclear energy.

Answer 2

NO first it was assumed that the total mass and energy of the universe were diffrent and constant but e=mc^2 converted mass to energy and vica-verse thus making energy, mass as same quantities. Still many scientists have doubt if this eq. is correct, it recently proved wrong, but soon it got corrected too.