Does anyone know anything about Buspirone?

Question

Like if it works and how long it takes before you feel the affects? Was it a good thing if you took it? I was perscribed only 5 mg to take twice a day and I am soooooo anxious with panic attacks that I am scared to take any meds. So please tell me any info you have. Thanks!!

Answer 1

I used to suffer with panic attacks and took buspirone for a short while. I found it started working after roughly 2 weeks and it did help although the problem i found was i could not orgasm during sex which i found weird. It also affected my sleep. Hope i could help, if your attacks are that bad just stick with them. If they don't help go straight back to your gp and demand something else because panic attacks are ****, i couldn't even go to the supermarket without freaking out.

Answer 2

Remember everyone reacts differently to medication. Buspar is an anti-anxiety, so it must work for some people or they wouldnt have it in that catagory. I took it and it u want to learn more about it go to my picture click on it and look at my questions asked, i asked some about buspar. i was put it feb 10 i gave it a mo and 1 wk, and it didnt work for me. made me worse actually, i shook all the time like i was cold and felt incredablt anxious at all times. i couldnt eat or sleep. i lost alot of weight which was the good thing about it except i felt like crap all the time. I talked to my therapist and she said buspar was so mild it was more like a placeebo affect then a med. i started zoloft and have felt a great amount of relieve. ive been of buspar and on zoloft almost two wks. the shaking stopped as soon as i stopped the buspar. it was weird. i really wanted it to work bc its a milder drug. just remember what didnt work for me may work for you. plus the only thing you can do is try it and hope for recovery, if it doesnt work in a mo u can try something new. if you have ant questions give me an e-mail. good luck.

Answer 3

Buspirone (brand-names Ansial®, Ansiced®, Anxiron®, Axoren®, Bespar®, BuSpar®, Buspimen®, Buspinol®, Buspisal®, Narol®, Spitomin®) is an anxiolytic agent and a serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the benzodiazepines, but it has an efficacy comparable to diazepam.

GO TO:

http://en.wikipedia.org/wiki/Buspirone

Answer 4

Buspar is a great medication for a lot of people to manage their anxiety. It is something that can take a couple of days to weeks to work though. You might want to get started now so you'll have relief soon, otherwise the panic attacks may continue to get worse!

Answer 5

Buspirone is a psychotropic drug with anxiolytic properties which belongs chemically to the class of compounds known as the azaspirodecanediones.

Buspirone shares some of the properties of the benzodiazepines and the neuroleptics, as well as demonstrating other pharmacological action. It attenuates punishment suppressed behavior in animals and exerts a taming effect, but is devoid of anticonvulsant and muscle relaxant properties and does not bind to the benzodiazepine/GABA receptor complex. Buspirone affects a variety of dopamine mediated biochemical and behavioral events, but is free of cataleptic activity. Buspirone has an affinity for brain D(2)-dopamine receptors, where it acts as an antagonist and agonist, and for the 5-HT(1A) receptors, where it acts as an agonist. Buspirone does not block the neuronal reuptake of monoamines and, on chronic administration, it does not lead to changes in receptor density in the models investigated. However, the mechanism of action of buspirone remains to be fully elucidated.

Buspirone is rapidly absorbed in man and undergoes extensive first pass metabolism. Following oral administration, low peak plasma levels of unchanged drug, of 1 to 6 ng/mL were observed 40 to 90 minutes after a single 20 mg dose. In a number of studies performed in healthy volunteers, the mean half-life of buspirone ranged from 2 to 3 hours up to approximately 11 hours with considerable variation in individual values. Multiple dose studies suggest that steady state plasma levels were usually achieved within a few days. Buspirone is metabolized primarily by oxidation, producing several hydroxylated derivatives and a pharmacologically active metabolite, 1-pyrimidinylpiperazine (1-PP). Peak plasma levels of 1-PP have been found to be higher than those of its parent drug and its half-life to be approximately double that of unchanged buspirone. In a single dose study using (14)C labeled buspirone, 29 to 63% of the dose was excreted in the urine within 24 hours, primarily as metabolites, while fecal excretion accounted for 18 to 38% of the dose. In man, approximately 95% of buspirone is plasma protein bound, but other highly bound drugs, e.g. phenytoin, propranolol and warfarin, are not displaced by buspirone from plasma protein in vitro. However, in vitro binding studies show that buspirone does displace digoxin.

The effect of food upon the bioavailability of buspirone was studied in 8 subjects. The area under the plasma concentration curve (AUC) and peak plasma concentration (C(max)) of unchanged buspirone increased by 84% and 116% respectively when the drug was administered with food, but the total amount of buspirone immunoreactive material did not change. The significance of this finding is not known, but it could indicate that food may decrease the presystemic clearance of buspirone.

Buspirone had no effect on hepatic microsomal enzyme activity when administered to rats for 5 days. In man, the effect of buspirone on drug metabolism or concomitant drug disposition has not been studied. The pharmacokinetics of buspirone in patients with hepatic or renal dysfunction, and in the elderly, has also not been clearly established.

Answer 6

I used to get "anxiety attacks" really bad in my early 20s, and for years, I thought surely I was going to have a heart attack, and too afraid to get on medicine for this once they told me it was "Anxiety Attack's" until one day I was working 2 jobs, raising 3 kids, and up late with paramedics in my apt., from having bad attacks, I finally gave in and went through "The human guinea pig" effect, for about 3 years!! They had me on paxil, buspar, elivil, prozac, you name it I tried it, until they finally put me, on diazepam.... But, I distinctly remember, the two, paxil, and buspar, the most, because with buspar, I thought I was going to have a "Heart attack" from the medicine, not the anxiety, (this time), and the paramedics had to stay in my apt, longer than ever, because I was so afraid for them to leave me alone!!! And so, I did not have a good normal experience with this drug, whatsoever!! And paxil, the same thing except I had to have my babysitter's husband drive me to the emergency room, twice!! From paxil.. I ended-up missing 2 days work, and the first day the doctor's told me I didn't give the medicine long enough to work, and sent me home to take it again so once I got to work, on the second day, before work started I told my co-worker, to tell the boss, I had to go to the emergency room once again, and miss work once again behind this new medicine, that's when I had to play "My own doctor!!" And tell them what would be best for me!! A friend gave me a valume many years ago, when I was having an anxiety attack so bad, she came out with the pill and told me take this, it'll help you! And I did, (this was before ever getting treated for it) and so, I remembered those days and her helping me that one time, and asked the doctor's if they could put me on valume and they gave me the generic form of it, so any of the pam's will work for me now.... Lorezepam, diazepam, or valume, I trust and nothing else anymore!! And I have to take 5mgs, 4 times a day, now.. to keep them away...... I didn't use to take them, except when I would feel an anxiety attack coming on, and my then , doctor told me to take all of them daily as prescribed in order not to get them!! And so I have to take all 4 of them every day, for years now...... And I highly recommend them to anyone who has anxiety.....so if the "Buspar" doesn't work out for you hun, definately request valume, or diazepam, or lorezepam, okay..... that's entirely up to you, I just want to help you, everyone's bodies are different, but its the "Mellowist" one I must say, after trying all of them, I have to say this one is the most successful one for getting rid of and keeping them away!!! The attack's I mean!!! Good Luck to you , hun!! Smile!!