2007-03-21 17:21:16 · 8 answers · asked by Micky 1 in Health ➔ Diseases & Conditions ➔ Other - Diseases
My mom took Vioxx for her carpel tunnel and tennis elbow. It was an anti-inflammatory. After they recalled it, she's never found a medication that was as good as it was for treating her symptoms.
I guess the side effects were really serious- like heart attack and even death.
2007-03-21 18:47:04 · answer #1 · answered by Anonymous · 0⤊ 0⤋
Rofecoxib (IPA: [rofəˈkɒksɪb]) is a nonsteroidal anti-inflammatory drug (NSAID) developed by Merck & Co. to treat osteoarthritis, acute pain conditions, and dysmenorrhoea. Rofecoxib was approved as safe and effective by the Food and Drug Administration (FDA) on May 20, 1999 and was subsequently marketed under the brand name Vioxx®, Ceoxx® and Ceeoxx®.
Rofecoxib gained widespread acceptance among physicians treating patients with arthritis and other conditions causing chronic or acute pain. Worldwide, over 80 million people were prescribed rofecoxib at some time.
On September 30, 2004, Merck voluntarily withdrew rofecoxib from the market because of concerns about increased risk of heart attack and stroke associated with long-term, high-dosage use. Rofecoxib was one of the most widely used drugs ever to be withdrawn from the market. In the year before withdrawal, Merck had sales revenue of US$2.5 billion from Vioxx.[citation needed]
Rofecoxib was available on prescription as tablets and as an oral suspension.
Adverse drug reactions
Aside from the reduced incidence of gastric ulceration, rofecoxib exhibits a similar adverse effect profile to other NSAIDs. Rofecoxib, however, does appear to increase the risk of adverse cardiovascular events (see below).
The chief mechanism proposed to explain rofecoxib's cardiotoxicity is the suppression of prostaglandin, an anti-clotting agent in the blood (Fitzgerald, 2004). COX-2 plays a role in the production of prostaglandin. Because Vioxx inhibits the COX-2 enzyme, prostaglandin production can decrease in endothelial cells and lead to an inefficiency in declumping and vasorelaxtion. Merck, however, argues that there was no effect on prostaglandin production in blood vessels in animal testing.[1] Other researchers have speculated that the cardiotoxicity may be associated with maleic anhydride metabolites formed when rofecoxib becomes ionised under physiological conditions. (Reddy & Corey, 2005)
Vioxx has also been associated with cardiovascular disease, renal (kidney) disease, and heart arrhythmia.
http://en.wikipedia.org/wiki/Vioxx
2007-03-21 17:36:01 · answer #2 · answered by uoptiger_79 4 · 0⤊ 0⤋
Wrongo, kiddies.
Vioxx is a medication that was predicted for ARTHRITIS and then it was found to cause severe complications with the heart.
I know this because an ex of mine had this exact thing happen. He went from being a big beautiful man to someone wasting away from this drug. It was totally bad news and he will die from it if he hasn't already.
2007-03-21 17:32:06 · answer #3 · answered by No name 2 · 0⤊ 0⤋
Vioxx was recalled by the manufacturer (Merck) in 2004. It was ALL over the news. People died from it. It caused too many heart problems.
http://www.fda.gov/fdac/features/2004/604_vioxx.html
***It was NOT for male enhancement. LOLOL It was an arthritis medication.
2007-03-21 17:23:29 · answer #4 · answered by Anonymous · 1⤊ 0⤋
It was the best arthritis medicine I have ever taken. If I could get it, I would still take it, side effects and all. It was awesome.
2007-03-21 17:30:05 · answer #5 · answered by stillsweetp 2 · 0⤊ 0⤋
What Is Vioxx
2017-02-22 05:12:18 · answer #6 · answered by Anonymous · 0⤊ 0⤋
It was anti-inflammatory drug used for Rheumatoid arthritis. To many problems with heart and cause strokes too.
2007-03-21 17:31:21 · answer #7 · answered by Joyce E 3 · 0⤊ 0⤋
it is used for male enhancement; there are lots of side effects ask a doctor
2007-03-21 17:24:21 · answer #8 · answered by bigmama 1 · 1⤊ 2⤋