Won't the polio antigen die due to the conc HCl in the stomach if it is administered orally?

Answer 1

The oral polio vaccine is a live-attenuated strain of polio, meaning that it is the actual virus, just a weakened form that cannot replicate in the human CNS -- i.e. it is not just the antigen. The complete virus is an enterovirus that is adapted to be able to withstand the gastric environment due to the properties of its capsid, and cannot be destroyed by heat -- thus, it is very resistant to harsh conditions, which allows it to colonize the GI tract and in fact be shed in the feces

Answer 2

Oral polio vaccine (OPV) has been the choice for routine immunization in over 120 countries that have eliminated poliomyelitis. OPV contains live attenuated polio virus that multiplies in mouth, ,pharynx , esophagus, larynx and trachea . This viral multiplication before reaching stomach makes the immunised child a source of live attenuated infection in upper GI and respiratory tract.to spread immunity to unimmunised children . This is called herd immunity.

Answer 3

i think of you ought to get vaccinated. There very is little threat in contact. The upsides thoroughly outweigh the downsides. I additionally do no longer think of toddlers who have not been vaccinated ought to be allowed in public faculties, that's how outbreaks take place. i do no longer think of that vaccines reason autism, nor do i think of that autism is transforming into extra regularly occurring, that's basically getting clinically determined extra many times. Dee W. : Take your tin foil hat off. You of direction understand that if all people shared your ideals, maximum folk would not stay plenty previous the age of 30. apart from once you're a "realist" and don't think of people ought to be messing with the organic order of issues, then how do you sustain your self. even in case your a vegan, the plant life you eat are in no way organic all plant life as we talk are guy-made hybrids. you will possibly ought to circulate decrease back to the 1600/1700's to locate plant life that have been relatively organic. of direction maximum farm animals these days have been genetically altered besides. the international hates hypocrites ma'am.