Gout is caused by a defect in metabolism that results in an overproduction of uric acid or a reduced ability of the kidney to eliminate uric acid. The exact cause of the metabolic defect is unknown. The condition may also develop in people with diabetes, obesity, sickle cell anemia, and kidney disease, or it may follow drug therapy that interferes with uric acid excretion.
Gout has 4 stages: asymptomatic (without symptoms), acute, intercritical, and chronic.
In acute gouty arthritis, symptoms develop suddenly and usually involve only one or a few joints. The pain frequently starts during the night and is often described as throbbing, crushing, or excruciating. The joint appears infected with signs of warmth, redness, and tenderness.
The attacks of painful joints may subside in several days, but may recur at irregular intervals. Subsequent attacks usually have a longer duration. Some people may progress to chronic gouty arthritis, while others may have no further attacks.
The risk is greater in men, postmenopausal women, and people who drink alcohol.
Symptoms
* Joint pain
o Begins suddenly
o Affects one or more joints (hip pain, knee pain, ankle pain, foot pain, shoulder pain, elbow pain, wrist pain, hand pain, or pain in other joints)
o The great toe, knee, or ankle joints are most often affected
* Joint swelling of the affected joints
* Stiffness of the joint
* The joint may be warm and red
* Fever may be present
* Skin lump which may drain chalky material
Signs and tests
A physical examination of the joints shows acute arthritis.
* Synovial fluid analysis shows uric acid crystals.
* Uric acid (blood test) may be elevated.
* Joint X-rays may be normal.
The following tests might also be helpful:
* Uric acid - urine
* Synovial biopsy
* Blood differential
Treatment
The goals of treatment are mainly to stop the pain and inflammation associated with the initial attack, and to prevent future attacks.
Colchicine is one of the medications that is effective in reducing the pain, swelling, and inflammation associated with acute gout attacks. The pain often subsides within 12 hours of starting treatment, and is completely relieved in 48 hours.
The medication works by decreasing the inflammation caused by uric acid crystals within the joint. However, it does not decrease the uric acid levels in the bloodstream. Daily use of colchicine or allopurinol helps prevent future attacks.
Non-steroidal anti-inflammatory drugs (NSAIDs) can be very effective in treating the pain and inflammation of an acute gout attack if taken soon after symptoms start.
Corticosteroids can also be very effective. Your doctor may inject the inflamed joint with steroids to relieve the pain.
Codeine or other analgesics may occasionally be prescribed for pain relief. Increased fluid intake prevents the formation of kidney stones.
Sometimes, a diet low in purines is prescribed. Organ meats, beer, wine, and certain types of fish contain high levels of purines.
Expectations (prognosis)
Adequate treatment of acute attacks allows people to live a normal life. The acute form of the disease may progress to chronic disease. Since uric acid is normally eliminated by the kidneys, chronic gout may lead to formation of uric acid kidney stones.
Complications
* Side effects of medications
* Chronic gouty arthritis
* Kidney stones
* Kidney dysfunction
Calling your health care provider
Call for an appointment with your health care provider if symptoms occur that are suggestive of acute gouty arthritis.
Prevention
The disorder itself may not be preventable, although some precipitating factors may include trauma, alcohol consumption, and dietary purines. Medications may reduce attacks in a person with gout.
2007-03-20 17:08:27
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answer #1
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answered by Gary S 4
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2016-09-16 23:21:36
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answer #2
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answered by Charlene 3
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Gout is a deposit/acid build up in your system caused by consuming too much meat or alcohol. Some people kidneys can not filter the acid out properly so it forms crystals in the joints. These are usually there for about 20 years before they give you trouble. Other causes are excess weight (associated with imbalanced diet) which is the case of younger people having gout. There are medical sites on the net such as 'real age' which can give you information on changing your diet to best deal with gout.
2007-03-20 17:08:55
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answer #3
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answered by obenypopstar 4
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Gout is a condition where uric acid crystals build up in the body.
This can happen in the area of the big toe and cause a lot of pain.
Our foods contain purines; some foods are higher in this than others.
The doctor may place you on a lower purine diet (of which they will usually provide you a list of foods to avoid. There is also medications that can lower the uric acid in the blood
Here an alternative way to cure gout?
2016-05-15 05:11:10
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answer #4
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answered by Anonymous
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Gout artheritis is an inflammation of the joints, usually the most furthest from the center of you body (toes and fingers). It is caused by uric acid crystals. Think of it sort of like having salt crystals built up and growing larger in the joints which makes it painful and almost crunchy stiff when moved. There is a few medications which will remove this uric acid from your body. It will heal almost 100% after a few weeks but you are predisposed to getting it again so its not uncommon to have to get the meds again if you feel the same symptoms in a year or more from now.
2007-03-20 17:08:40
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answer #5
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answered by n_m_young 4
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Yes, there is medication for gout which is a form or arthritis. I'm providing you with a link to information. And, yes a woman with gout can get pregnant.
2007-03-20 17:10:14
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answer #6
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answered by Neil L 6
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The Smashing Pumpkins- Silverfuck
2016-03-16 23:54:29
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answer #7
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answered by Anonymous
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It is often related to the overconsumption of alcohol; mine went away after I quit drinking. They used to treat it with Colchicine, a soluble alkaloid, but that was many years ago. Drink plenty of water, anyway, and see your doctor.
2007-03-20 17:09:55
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answer #8
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answered by CLICKHEREx 5
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