Parkinson's disease
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Parkinson's disease
Classification & external resources
Illustration of the Parkinson disease by Sir William Richard Gowers from A Manual of Diseases of the Nervous System in 1886
ICD-10 G20.
ICD-9 332
DiseasesDB 9651
MedlinePlus 000755
eMedicine neuro/304 neuro/635 in young
pmr/99 rehab
Parkinson's disease (also known as Parkinson disease or PD) is a degenerative disorder of the central nervous system that often impairs the sufferer's motor skills and speech.
Parkinson's disease belongs to a group of conditions called movement disorders. It is characterized by muscle rigidity, tremor, a slowing of physical movement (bradykinesia), and in extreme cases, a loss of physical movement (akinesia). The primary symptoms are the results of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Secondary symptoms may include high level cognitive dysfunction and subtle language problems. PD is both chronic and progressive.
PD is the most common cause of parkinsonism, a group of similar symptoms. PD is also called "primary parkinsonism" or "idiopathic PD" ("idiopathic" meaning of no known cause). While most forms of parkinsonism are idiopathic, there are some cases where the symptoms may result from toxicity, drugs, genetic mutation, head trauma, or other medical disorders.
2007-03-19 00:11:02
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answer #1
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answered by Anonymous
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Parkinson's disease is a disease of the Central Nervous System/Neurological disorder (Substantia Nigra in the brain). Here there is an imbalance of a chemical called dopamine in the brain.
Think of this as a disease 'at rest' (resting tremors)......these are tremors that occur unintentionally. Also associated with rigidity, mask like facial features, slow gait, dementia etc
Treatment is basically medication to improve the dopamine levels in brain.
***Yeah, this is what Micheal J Fox has.
2007-03-19 00:22:39
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answer #2
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answered by Anonymous
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Parkinson’s disease is the progressive disorder of nervous system affecting movements. It develops gradually starting with the barely noticeable tremors but in the later stage it is associated with frequent body stiffness and slowing or complete loss of movement.
Parkinson’s is a type of neurodegenerative disorder involving malfunctioning or death of vital nerve cells called neurons in the brain. The substantial cause of this neuronal degeneration is said to be; decreased secretion of a hormone “Dopamine”. This dopamine is involved in signal transmission process controlling and coordinating bodily movements. The progress of PD is associated with little or no production of dopamine thus unabling a person to control muscular movements normally. Along with dopamine, clumps of proteins in brain cells are also said to be a prime suspect in Parkinson’s. They are affecting the non motor functions of the brain such as sense of smell, sleep regulation etc.
With the new invention of stem cells it is possible to proactively alter effects of the disorders and live a full, happy, healthy life. Having the potential to significantly impact the development of diseased state these stem cells can create dopamine producing cells thus enhancing normal communication between neurons. visit advancells.com to know more about this disease and its treatment.
2014-12-05 22:27:42
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answer #3
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answered by Priya 1
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Parkinson's disease affects the way you move. It happens when there is a problem with certain nerve cells in the brain.
Normally, these nerve cells make an important chemical called dopamine. Dopamine sends signals to the part of your brain that controls movement. It lets your muscles move smoothly and do what you want them to. When you have Parkinson’s, these nerve cells break down. Then you no longer have enough dopamine, and you have trouble moving the way you want to.
Parkinson’s is progressive, which means it gets worse over time. But usually this happens slowly, over a period of many years. And there are good treatments that can help you live a full life.
What causes Parkinson's disease?
No one knows for sure what makes these nerve cells break down. But scientists are doing a lot of research to look for the answer. They are studying many possible causes, including aging and poisons in the environment.
Abnormal genes seem to lead to Parkinson's disease in some people. But so far, there is not enough proof to show that it is inherited.
What are the symptoms?
The four main symptoms of Parkinson’s are:
Tremor, which means shaking or trembling. Tremor may affect your hands, arms, legs, or head.
Stiff muscles.
Slow movement.
Problems with balance or walking.
Tremor may be the first symptom you notice. It is one of the most common signs of the disease, although not everyone has it. Tremor often starts in just one arm or leg or only on one side of the body. It may be worse when you are awake but not moving the affected arm or leg. It may get better when you move the limb or you are asleep.
In time, Parkinson’s affects muscles all through your body, so it can lead to problems like trouble swallowing or constipation. In the later stages of the disease, a person with Parkinson’s may have a fixed or blank expression, trouble speaking, and other problems. Some people also have a decrease in mental skills (dementia).
People usually start to have symptoms between the ages of 50 and 60, but in some people symptoms start earlier.
How is Parkinson's disease diagnosed?
Your doctor will ask questions about your symptoms and your past health and will do a neurological exam. A neurological exam includes questions and tests that show how well your nerves are working. For example, your doctor will watch how you move, check your muscle strength and reflexes, and check your vision. He or she will also ask questions about your mood.
There are no lab tests that can help your doctor know that you have Parkinson’s. But you may have tests to help your doctor rule out other diseases that could be causing your symptoms. For example, you might have an MRI to look for signs of a stroke or brain tumor.
How is it treated?
At this time, there is no cure for Parkinson's disease. But there are several types of medicines that can control the symptoms and make the disease easier to live with.
Levodopa (also called L-dopa) is the best drug for controlling symptoms of Parkinson's disease. But it can cause problems if you use it for a long time or at a high dose. For this reason, many doctors use other medicines to treat people in the early stages of the disease. This lets them delay the use of levodopa and postpone the side effects.
You may not even need treatment if your symptoms are mild. Your doctor may wait to prescribe medicines until your symptoms start to get in the way of your daily life. Your doctor will adjust your medicines as your symptoms get worse. You may need to take several medicines to get the best results.
In some cases, a treatment called deep brain stimulation may also be used. For this treatment, a surgeon places wires in your brain. They stimulate an area in your brain that affects movement.
There are many things you can do at home that can help you stay as independent and healthy as possible. Eat healthy foods. Get the rest you need. Make wise use of your energy. Get some exercise every day. Physical therapy and occupational therapy can also help.
2007-03-19 02:30:15
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answer #4
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answered by Krystal 3
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well alzheimers disease is more from arabs the indain part of the world parkision more in the uk jokes and also the U.S.A thats a main differnace now the main symptons is that parkison is none stop shaking cuz thats where them kind of cells attack all round the body alzheimers just attacks the brain like arthythoiles that attacks a specfic part like say your arm or leg but if you have rhymatsim arthytoiles then it attacks all over u most freqentl constant too so it just how and how long and how many and how few the cells specfil loactions are and how many to attack whch parts now these dieases are main so there is lots o batrieca bad cells so it will attack bad in allround u body except for alzheimer and arthyoiles cuz there have specfic part unlike the other 2 parksion diease and rhymatism arthyoiles
2016-03-16 22:53:18
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answer #5
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answered by Anonymous
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That sounds like Parkinsons. There are other things that you can see - "pill rolling tremor", small rapid steps, freezing at the joint between 2 different floor covers (ie. linoleum and carpet)
2007-03-19 00:57:00
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answer #6
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answered by Buzz s 6
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the person loses his control over his nervous system
and the n his limbs jerk involuntary because of which he dies as he gets exhausted
dun dun dun dun duuuuuuuuuunnnnnnnnnn
2007-03-19 00:23:51
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answer #7
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answered by Anonymous
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