What is the proposed Mechanism Of Action (MOA) of acetaminophen-induced hepatoxicity? This is urgent! thanks.

Answer 1

Acetaminophen can deplete the liver's supply of Glutathione - a critical antioxidant. When glutathione is depleted, liver cells rapidly die via necrosis.

Standard treatment for acetaminophen induced hepatotoxicity is supplementation with NAC (N-Acetyl Csyteine) the rate-limiting precursor for glutathione synthesis.

Answer 2

Acetaminophen Moa

Answer 3

to respond to your question first: sure, I do think of he's incorrect. Had he in basic terms called out for greater suitable anti terrorist operations by ability of the Israel protection Forces then i might have not have been given any objections. yet for this reason he went previous that. And now for you: would I tremendously recommend you end being deceptive on the subject of the subject? I study the item you appropriate to. He pronounced (direct quote): "putting the youngsters of the terrorist who carried out the attack interior the Mercaz Harav yeshiva from a tree." He did no longer say what you pronounced. He did no longer say all Arab toddlers, he pronounced the youngsters of a particular terrorist. Granted, it incredibly is likewise incorrect (on account that his toddlers have not carried out any terrorist assaults and that i'm no longer even beneficial he had childrens) yet you're nevertheless misquoting. I evaluate this deceptive on account which you're certainly attempting to make him sound lots worse. additionally, the JDL is a tiny business enterprise that has little impression on something. and finally, he looks to have been roundly condemned by ability of businesses at the same time with "Musawa center for Arab Rights in Israel". i think it incredibly is going to be a protracted time coming while they are going to certainly condemn some distance worse statements coming from Islamic leaders in Gaza.