The symptoms are suggestive of Parkinson's Disease. Other symptoms include micrographia (small and illegible writing due to the tremor) and a shuffling gait.
This condition involves a deficiency of dopamine in the basal ganglia of the brain.
Hope that helps!
Cheers!
2007-03-14 18:43:30
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answer #1
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answered by Amuse Bouche 4
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It is Parkinson's disease(also known as Parkinson disease or PD). It is a degenerative disorder of the central nervous system that often impairs the sufferer's motor skills and speech.
Parkinson's disease belongs to a group of conditions called movement disorders. It is characterized by muscle rigidity, tremor, a slowing of physical movement (bradykinesia), and in extreme cases, a loss of physical movement (akinesia). The primary symptoms are the results of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Secondary symptoms may include high level cognitive dysfunction and subtle language problems. PD is both chronic and progressive.
Symptoms
Parkinson disease affects movement (motor symptoms). Typical other symptoms include disorders of mood, behavior, thinking, and sensation (non-motor symptoms). Individual patients' symptoms may be quite dissimilar and progression of the disease is also distinctly individual.
Motor symptoms
The cardinal symptoms are:
tremor: normally 4-7Hz tremor, maximal when the limb is at rest, and decreased with voluntary movement. It is typically unilateral at onset. This is the most apparent and well-known symptom, though an estimated 30% of patients have little perceptible tremor; these are classified as akinetic-rigid.
rigidity: stiffness; increased muscle tone. In combination with a resting tremor, this produces a ratchety, "cogwheel" rigidity when the limb is passively moved.
bradykinesia/akinesia: respectively, slowness or absence of movement. Rapid, repetitive movements produce a dysrhythmic and decremental loss of amplitude. Also "dysdiadokinesia", which is the loss of ability to perform rapid alternating movements
postural instability: failure of postural reflexes, which leads to impaired balance and falls.
Other motor symptoms include:
Gait and posture disturbances:
Shuffling: gait is characterized by short steps, with feet barely leaving the ground, producing an audible shuffling noise. Small obstacles tend to trip the patient
Decreased arm swing: a form of bradykinesia
Turning "en bloc": rather than the usual twisting of the neck and trunk and pivoting on the toes, PD patients keep their neck and trunk rigid, requiring multiple small steps to accomplish a turn.
Stooped, forward-flexed posture. In severe forms, the head and upper shoulders may be bent at a right angle relative to the trunk (camptocormia).
Festination: a combination of stooped posture, imbalance, and short steps. It leads to a gait that gets progressively faster and faster, often ending in a fall.
Gait freezing: "freezing" is another word for akinesia, the inability to move. Gait freezing is characterized by inability to move the feet, especially in tight, cluttered spaces or when initiating gait.
Dystonia (in about 20% of cases): abnormal, sustained, painful twisting muscle contractions, usually affecting the foot and ankle, characterized by toe flexion and foot inversion, interfering with gait. However, dystonia can be quite generalized, involving a majority of skeletal muscles; such episodes are acutely painful and completely disabling.
Speech and swallowing disturbances
Hypophonia: soft speech. Speech quality tends to be soft, hoarse, and monotonous. Some people with Parkinson's disease claim that their tongue is "heavy".
Festinating speech: excessively rapid, soft, poorly-intelligible speech.
Drooling: most likely caused by a weak, infrequent swallow and stooped posture.
Non-motor causes of speech/language disturbance in both expressive and receptive language: these include decreased verbal fluency and cognitive disturbance especially related to comprehension of emotional content of speech and of facial expression[5]
Dysphagia: impaired ability to swallow. Can lead to aspiration, pneumonia, and ultimately death.
Other motor symptoms:
fatigue (up to 50% of cases);
masked faces (a mask-like face also known as hypomimia), with infrequent blinking;[6]
difficulty rolling in bed or rising from a seated position;
micrographia (small, cramped handwriting);
impaired fine motor dexterity and coordination;
impaired gross motor coordination;
Poverty of movement: overall loss of accessory movements, such as decreased arm swing when walking, as well as spontaneous movement
Hope this helps!
2007-03-15 08:23:09
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answer #2
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answered by it's_just_me 3
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