during blood transfusion, what happens to the donor's dna present in the blood?

Answer 1

No, a person who received a whole blood transfusion would not display detectable amounts of the donor's DNA profile
The parts of blood involved in transfusion are serum, platelets, plasma and corpuscles (red blood cells & white blood cells). White blood cells are removed by filtration (Leukoreduction) and as this is the only bit with DNA in it, there's no chance of problems.
Due to certain limitations, whole blood transfusions are rare; most blood transfusions today are done with what's called packed red blood cells (erythrocytes). Erythrocytes contain no DNA, having lost their nuclei during maturation.
White blood cells, (leukocytes), contain nuclei and are the agents that provide a DNA profile from blood. In whole blood transfusions, the whole soup is transfused from one person to another.
In actual observation, the DNA profile of a blood donor has not been detected in the peripheral blood of a recipient, regardless of how much was transfused. In one study, a woman was transfused with 14 units of blood (four whole, ten packed red cells), while a man received 13 units (four whole, nine packed red cells). In both cases, neither individual had detectable levels of the foreign DNA profile

Answer 2

Red blood cells do not have DNA. The surface of red blood cells have two flag poles. This first carries the A or B flag, both A and B or neither = O The second either has the Rhesus flag or it does not. Your body will attack any cell with a foreign flag (a flag it does not have) If you are O (no A or B flags) Negative (no Rhesus flag) you will attack any cells who are not the same. If you are AB Positive, you will be OK with any blood given. O negative is known as universal donor as there are no flags to object to. AB Positive is the universal recipient as any blood given will be accepted. It is all about the blood given being compatible withe receivers blood. Although the blood being given can contain antibodies to the recipient it will not do any major harm as it is just a pint or two of blood and does not have the resources of a whole body to mount an attack on the receivers blood. To complicate matters there is a blood type called the Bombay Blood group, which does not even have the flagpoles. These make good donors but people with this blood type will attack even O negative donations.

Answer 3

There's not much DNA in blood. The white blood cells will probably be destroyed by your body's immune system, but the red blood cells have no DNA. When getting a transfusion, what's important are the red blood cells.

Answer 4

the red blood cells don't have a nucleus.. n tats where the DNA is present in the normal cells.. so there is no problem wit that.. n as for the white blood cells..it just has a life span of 13-20 days.. so after that the cell is destroyed.. n the platelets also live only for 8-10 days.. so the donor DNA also does not stay much long in our body.. n they do not cause any problem in our body as long as they remain there.. hope tat answers ur doubt..

Answer 5

A blood donor`s DNA does not influence the recepient. After the life span of donor`s blood constituents ends the recepient is normal as usual.

Answer 6

It's actually very unusual to get whole blood transfusions, and even then there's little DNA, mostly in white blood cells. Just like your own blood components, but faster, they're torn down, metabolized, and the end-products eventually wind up in your poop and a little in your pee.

Answer 7

we basically transfuse leuko reduced RBCs nowadays. the white blood cells are filtered out, leaving only the packed red blood cells. red blood cells have no nucleus, and since DNA can only be found in the nucleus of a cell, then, there really is no DNA transfused with the cells.

Answer 8

No DNA is blood, unless you got your blood from a chicken (they have nucleated blood cells). Additionally you can't just inject DNA into someone and have it automatically incorporated into your own. This a complicated process to achieve and makes gene therapy so complex.

Answer 9

let me tell you...Red Blood Corpucles.. which constitutes blood does not contain DNA...and the White Blood Ccorpuscles which contain are recognised as antigen and destroyed...

Answer 10

you are now carrying it, but not enough to change yours, scary isn't it?