Has anyone ever had a bad reaction from drinking grapefruit juice while on prescription antidepressants??

Answer 1

Grapefruit juice provides many nutrients, such as vitamin C and lycopene. But chemicals in grapefruit interfere with the enzymes that break down (metabolize) certain drugs in your digestive system. This can result in excessively high levels of these drugs in your blood and an increased risk of serious side effects.

The exact chemicals in grapefruit juice that cause this interaction aren't known. But these chemicals are present in the pulp and peel of grapefruit as well as in the juice. For this reason, any grapefruit product — including dietary supplements that contain grapefruit bioflavonoids — can interact with certain medications. If you avoid grapefruit, you may also want to avoid tangelos, a hybrid grapefruit, and Seville oranges, a type of bitter orange often used to make marmalade and compotes. They may have a similar effect.

Answer 2

I haven't personally but some medications should not be taken with grapefruit juice because the juice has certain chemicals in it that block digestion and metabolism of certain types of drugs and can intensify the effect of them.
I have seen prescription bottles that have a sticker on the side that clearly says "Do not take within 2 hours of ingesting grapefruit juice" and then there is a small icon of a halved grapefruit next to it.

I found a source that supports this information.
http://www.headachedrugs.com/archives/grapefruit.html

"Nariginin, a bioflavenoid in grapefruit juice is suspected to be influencing drug metabolism".

Various classes of prescription medications should not be taken at the same time with grapefruit juice. Such classes include some sedatives, antianxiety agents, calcium channel blockers, certain statins (for high cholesterol), and antidepressants.

Answer 3

You have to be extremely careful when drinking grapefruit juice while on prescription medication! The reason is that there is a naturally occurring compound in grapefruit juice which will cause the dosage of medication you are taking to act like it has been TRIPLED in your body!

Please do not drinkl grapefruit juice at the same time as taking prescription meds.....

Answer 4

For some reason grapefruit juice can cause unwanted side effects in medications., For instance there is a sleeping pill that you can't take it with.

Answer 5

Call your pharmacy. It should not "kill" you BUT... you should not take any medication with grapefruit juice, something like the grapefruit juice makes the medication desolve faster or something to that affect. Call your pharmacy or any pharmacy in your area and ask.. they will tell you to not take any meds with grapefruit juice.

Answer 6

I don't drink grapefruit juice myself, but my dad is on oral diabetes meds and was told to NEVER drink this while on them. Talk to your doctor about any effects that you are having.

Answer 7

Grapefruit juice is probably OK.

However, you should not have mixed it with half a bottle of Vodka.

Answer 8

yes

Answer 9

YES...They DO NOT mix....