does taking advil everyday harm your stomach?

Answer 1

Possibly, it is a COX Inhibitor, Like Aspirin, but Damage Less Probable than With Aspirin, Aspirin is an Acid, a big Difference Between the Two is that Inhibition By Aspirin is Irreversible, Ibuprofen, Reversible.


Not to Leave you High and Dry, Here Are the Adverse Reactions:

The most frequent type of adverse reaction reported with ibuprofen is gastrointestinal (GI) with 4—16% of patients in controlled clinical trials reporting one or more GI adverse reactions. In controlled trials, the overall incidence of GI adverse reactions associated with ibuprofen was about half that seen aspirin- or indomethacin-treated patients. Adverse GI effects reported in up to 9% of patients receiving ibuprofen include anorexia, nausea/vomiting, epigastric/abdominal pain, dyspepsia, constipation, diarrhea, gastritis, melena, and flatulence. Severe GI effects occur with a frequency of less than 1% and include gastric ulceration with or without GI bleeding, peptic ulcer disease, or GI perforation. These severe adverse reactions often occur in the absence of early GI manifestations. The risk of severe GI events is increased by the presence of the following factors: history of peptic ulcer disease or GI bleed, smoking, alcohol usage, concomitant usage of anticoagulants, or oral corticosteroids, older age, poor general health status, and NSAID duration of use. Gastrointestinal bleeding or erosive gastritis can be minor or life-threatening and may result from a combination of direct irritant action on the stomach mucosa and a prolonged bleeding time, due to changes in platelet aggregation. Older patients appear to be greater affected by GI ulceration or bleeding; most fatal GI events occur in older or debilitated patients. Occult GI bleeding occurs in many patients and is not necessarily correlated with GI distress. While the amount of blood lost is usually not significant, blood loss can result in iron deficiency anemia. Patients on prolonged therapy should undergo regular blood monitoring. Use the lowest effective dose of ibuprofen for the shortest possible duration. Discontinue ibuprofen if a serious GI adverse event is suspected.

Rare cases of esophagitis have been reported in patients receiving ibuprofen tablets. Ibuprofen-induced esophagitis is characterized by sudden onset odynophagia, pyrosis (heartburn), retrosternal pain, and dysphagia. Severe complications such as esophageal ulceration, esophageal stricture, bleeding, and perforation have been reported rarely. Risk factors for ibuprofen-induced esophageal effects include taking the medication without water and at night. Symptoms usually resolve within days to weeks after stopping the medication.

Pancreatitis has been reported in < 1% of patients on ibuprofen.

Altered vision (blurred vision or visual impairment) has been reported infrequently (< 1%) in patients receiving ibuprofen. Vision generally improves when the drug is discontinued. The mechanism for visual disturbances is unclear. Other changes in the special senses include tinnitus (< 3%) and hearing loss (< 1%).

Ibuprofen has been associated with acute renal failure (unspecified), decreased creatinine clearance, polyuria, azotemia, cystitis, and hematuria (< 1%). It is well known that vasodilatory renal prostaglandins and the potent vasoconstrictor angiotensin II work in concert to maintain renal blood flow. Inhibition of renal prostaglandins by NSAIDs can cause renal insufficiency. This problem can be manifest as hyperkalemia, hyperuricemia, or azotemia. With some NSAIDS, renal papillary necrosis, nephrotic syndrome, hematuria, proteinuria, and interstitial nephritis have been reported. Fluid retention and edema (peripheral edema) have been reported in 1—3% of patients receiving ibuprofen. Hypertension and congestive heart failure have been reported < 1% during ibuprofen therapy.

NSAIDs have been associated with hepatotoxicity such as hepatitis or jaundice. Usually, this is an infrequent occurrence, but patients should be monitored closely if elevated hepatic enzymes are observed during therapy.

Ibuprofen has been shown to cause platelet dysfunction; this effect, however, is transient and reversible. Hematologic effects (< 1%) due to ibuprofen include neutropenia, agranulocytosis, aplastic anemia, hemolytic anemia, pancytopenia, and thrombocytopenia.

Rash (unspecified), including maculopapular rash, and pruritus have been reported in 1—3% of patients taking ibuprofen. Other dermatologic reactions occur less frequently (< 1%), including bullous rash, urticaria, erythema multiforme, Stevens-Johnson syndrome, alopecia, photosensitivity reactions, and toxic epidermal necrolysis. Exfoliative dermatitis, a serious and potentially fatal skin reaction, has been reported with other NSAIDs and may occur with ibuprofen. Patients should be instructed to discontinue the medication and contact their health care provider if erythema, rash, blisters, or related skin reactions develop. Other allergic-type reactions that have been reported with ibuprofen use include angioedema and Henoch-Schonlein vasculitis, although the incidence of these rare reactions is unknown.

Ibuprofen may cause bronchospasm, dyspnea, and wheezing in patients with asthma (see Contraindications). The proposed mechanism of nonsteroidal anti-inflammatory drug-sensitive asthma is excessive production of cysteinyl leukotrienes. A single exposure could induce lung function deterioration, as the reaction is not thought to be of an allergic hypersensitivity nature. Likewise, subsequent exposures should not result in escalating bronchospasm severity.

Central nervous system adverse effects (< 9%) associated with ibuprofen include dizziness, headache, and nervousness. Overuse of ibuprofen by headache-prone patients frequently produces drug-induced rebound headache accompanied by dependence on symptomatic medication, tolerance (refractoriness to prophylactic medication), and withdrawal symptoms. In this case, overuse of ibuprofen has been defined as taking 3 or more doses per day more often than 5 days per week.[4043] The frequency of use may be more important than the dose. Features of a rebound headache include morning headache, end-of-dosing interval headache, or headache improvement with discontinuation of overused medication. Stopping the symptomatic medication may result in a period of increased headache and then headache improvement. Analgesic overuse may be responsible for the transformation of episodic migraine or episodic tension headache into daily headache and may perpetuate the syndrome.[4043]

Aseptic meningitis has been reported rarely with NSAID therapy. Ibuprofen has been the most common NSAID implicated in this adverse reaction; however, cases have been reported with sulindac, naproxen, tolmetin, diclofenac, ketoprofen, rofecoxib, and piroxicam. Aseptic meningitis from one NSAID does not preclude use of another NSAID; most patients can be treated with another drug without incident. However, one patient with Sjogren's syndrome experienced aseptic meningitis after receipt of naproxen, ibuprofen, and rofecoxib at different times; aseptic meningitis developed about a week after each drug exposure, and the symptoms abated roughly 2 days following each drug cessation.[4420] The occurrence of aseptic meningitis is not related to NSAID chemical class or prostaglandin inhibition. A Type III or IV immunological hypersensitivity reaction is the proposed mechanism of action. Drug-induced aseptic meningitis usually occurs shortly after drug initiation but can occur after years of drug usage. Although NSAID-induced aseptic meningitis is primarily reported in patients with systemic lupus erythematosus (SLE), healthy patients and patients with other disease states such as ankylosing spondylitis, connective tissue disease, osteoarthritis, and rheumatoid arthritis have developed NSAID-induced aseptic meningitis. Symptoms of aseptic meningitis include confusion, drowsiness, general feeling of illness, severe headache, nausea, nuchal rigidity, and photophobia. As aseptic meningitis is a diagnosis of exclusion, the suspected drug should be discontinued and not restarted unless a rechallenge is desired.

Ibuprofen has been associated infrequently (< 1%; without causal relationship) with the development of pseudotumor cerebri (benign intracranial hypertension).
[ Last revised: 1/22/2007 7:54:00 PM ]

Answer 2

1

Answer 3

You really should not take advil (ibuprofen) like it's candy. It's a drug, a chemical, and it can have adverse side effects. As someone else has mentioned it can cause bleeding of the stomach. It can also raise your blood pressure and increase your risk for heart attack and stroke. You and your friend need to immediately stop taking a bunch of advil just for fun, it's not safe.

Answer 4

advil everyday harm stomach

Answer 5

Yes it causes alot of health problems if taken daily.Ulcers,asitds,liver and kidney damage etc... Take it daily only under doctors order.

Answer 6

Especially if you take it with too little liquid.
I take any analgesic like that with milk.

Answer 7

Worse.
It can blow out your kidneys.
You're not supposed to use this stuff habitually.

Answer 8

It fried my liver.