Definitely. It's an opiate (it's in the same class of drugs as morphine and codeine).
2007-02-25 23:57:19
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answer #1
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answered by Alli 7
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Methadone is an opioid, it's true. However, contrary to what the pharmacy tech posted, methadone does not show up common urine test for opiates. The Dept of Transportation (and those doctors' offices who do drug testing for companies after someone wrecks a forklift, for example) uses tests which look for the "Federal Five" drugs (i.e., ones most likely being abused or trafficked): opioids, benzodiazepines, cocaine, THC, and methamphetamines/amphetamines. The cutoff limit for these drugs is exceptionally high (along the order of 3000ng/mL for opioids and benzos, somwhere like 300ng/mL for THC) meaning people can be seriously "baked" and still not lose their jobs driving tractor trailers or harbor pilot boats, etc. Indeed, if the testing limits were more like what you see in pain management clinics, there would be very little highway transportation taking place because all the truckers who take a little Xanax to get to sleep and then a little Ritalin to wake back up would be busted.
Unless a person's urine is sent to a laboratory capable of specifically testing for methadone (usually via gas chromatography or mass spectroscopy), methadone is not likely to show up on the urine test. Even oxycodone (found in Percocet and OxyContin) does not routinely show up on many of the plain-Jane "dipstick" immunoassay tests for drugs in urine. Those tests only really look for opioids like morphine or codeine which have naturally occurring molecules. The semisynthetics and synthetics like oxycodone, fentanyl, or methadone just don't show up well on the immunoassay tests. Even with GC/MS testing at specialized labs, the fact that methadone has a variable half life and even more variable elimination (due to pH-dependent resorption in the kidney's structures) make it absolutely unpredictable as to HOW MUCH should make it through. There are labs that claim to be able to tell you how much (by mass/volume) methadone should be in a person's urine based on their dose, time since administration, and height and weight. That is competely illogical.
P.S. I prescribe opioids all day, every day, as a nurse practitioner in a pain management practice. I do urine testing on patients all day, too, and interpret the results of as many as 150 tests per month.
2007-02-27 12:58:41
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answer #2
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answered by James M 1
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Methadone accounts for 5% of the dose in the 24 hour urine following a single 15 mg oral dose. . Excretion rates of the unchanged methadone increased to 22% of the dose only in acidic urine. In maintenance subjects, 24 hour urinary methadone may account for 5-50% of the dose, with large individual variations due to urine pH, urine volume, dose, and rate of metabolism.Urine test therefore shows up in urine test
2007-02-25 16:45:12
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answer #3
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answered by J.SWAMY I ఇ జ స్వామి 7
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