help help help!!?

Question

i require product details for these certain medicines from Glaxo Smithkline for a job interview .
1.Zantac
2.Seretide
3.Flixotide


the one that anwnswers them all gets TEN POINTS

Answer 1

Zantac
Generic Name: ranitidine (ra NI ti deen)

Brand Names: Zantac, Zantac 150, Zantac 300, Zantac 300 GELdose, Zantac 75, Zantac EFFERdose, Zantac GELdose,


What is the most important information I should know about Zantac?
Before using this medication, tell your doctor if you are allergic to any drugs, or if you have kidney disease, liver disease, or porphyria.

Using Zantac may increase your risk of developing pneumonia. Symptoms of pneumonia include chest pain, fever, feeling short of breath, and coughing up green or yellow mucous. Talk with your doctor about your specific risk of developing pneumonia.

Zantac granules and effervescent tablets must be dissolved in water before you take them.

Your doctor may recommend an antacid to help relieve pain. Carefully follow your doctor's directions about the type of antacid to use, and when to use it. Avoid drinking alcohol. It can increase the risk of damage to your stomach. It may take up to 8 weeks of using this medicine before your ulcer heals. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 6 weeks of treatment.

What is Zantac?
Zantac is in a group of drugs called histamine-2 blockers. Zantac works by reducing the amount of acid your stomach produces.

Zantac is used to treat and prevent ulcers in the stomach and intestines. It also treats conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome. Zantac also treats gastroesophageal reflux disease (GERD) and other conditions in which acid backs up from the stomach into the esophagus, causing heartburn.

Zantac may also be used for conditions other than those listed in this medication guide.


What should I discuss with my healthcare provider before using Zantac?
Do not use this medication if you are allergic to Zantac.
Before using Zantac, tell your doctor if you are allergic to any drugs, or if you have:

kidney disease;
liver disease; or
porphyria.

If you have any of the conditions listed above, you may not be able to use Zantac or you may need a dosage adjustment or special monitoring during treatment.

Zantac effervescent tablets may contain phenylalanine. Talk to your doctor before using this form of Zantac if you have phenylketonuria (PKU).

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Zantac passes into breast milk. Do not take Zantac without telling your doctor if you are breast-feeding a baby.
Using Zantac may increase your risk of developing pneumonia. Symptoms of pneumonia include chest pain, fever, feeling short of breath, and coughing up green or yellow mucous. Talk with your doctor about your specific risk of developing pneumonia.


How should I take Zantac?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take each Zantac tablet with a full glass of water.
Your doctor may recommend an antacid to help relieve pain. Carefully follow your doctor's directions about the type of antacid to use, and when to use it.

Do not crush, chew, or break the rantidine effervescent tablet, and do not allow it to dissolve on your tongue. The 25-milligram effervescent tablet must be dissolved in at least 1 teaspoon of water before swallowing. The150-milligram effervescent tablet should be dissolved in 6 to 8 ounces of water.
Allow the tablet to dissolve completely in the water, and then drink the entire mixture. If you are giving this medicine to a child, you may draw the liquid mixture into a medicine dropper and empty the dropper into the child's mouth.

Zantac granules should be mixed with 6 to 8 ounces of water before drinking.

Measure the liquid form of Zantac with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

It may take up to 8 weeks of using this medicine before your ulcer heals. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 6 weeks of treatment.
This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using Zantac.

Store Zantac at room temperature away from moisture, heat, and light.

What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.


What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
Symptoms of a Zantac overdose may include lack of coordination, feeling light-headed, or fainting.


What should I avoid while taking Zantac?
Avoid drinking alcohol. It can increase the risk of damage to your stomach.

What are the possible side effects of Zantac?
Stop using Zantac and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:
chest pain, fever, feeling short of breath, coughing up green or yellow mucous;

easy bruising or bleeding, unusual weakness;

fast or slow heart rate;

problems with your vision;

fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Other, less serious side effects may be more likely to occur, such as:

headache (may be severe);

drowsiness, dizziness;

sleep problems (insomnia);

decreased sex drive, impotence, or difficulty having an orgasm; or

swollen or tender breasts (in men);

nausea, vomiting, stomach pain; or

diarrhea or constipation.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.


What other drugs will affect Zantac?
Before taking Zantac, tell your doctor if you are taking triazolam (Halcion). You may not be able to use Zantac, or you may need dosage adjustments or special tests during treatment.

There may be other drugs that can affect Zantac, or be affected by Zantac. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.


Where can I get more information?
Your pharmacist has information about Zantac written for health professionals that you may read.
What does my medication look like?
Ranitidine is available with a prescription under the brand name Zantac. It is also available over the counter under the brand name Zantac 75. Other brand and generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

Zantac 150 mg Tablets--five-sided, peach-colored, film-coated tablets

Zantac 25 mg and 150 mg EFFERdose Tablets--round, white, flat-faced, beveled tablets

Zantac 150 mg EFFERdose Granules--white/pale-yellow granules

Zantac 300 mg Tablets--capsule-shaped, yellow, film-coated tablets

Zantac 300 mg Capsule--beige, soft-gelatin capsules

Zantac Syrup 15 mg/mL-clear, peppermint-flavored liquid


Seretide is indicated in the regular treatment of asthma where use of a combination product (long-acting beta-2-agonist and inhaled corticosteroid) is appropriate: - patients not adequately controlled with inhaled corticosteroids and as needed inhaled short acting beta-2-agonist or - patients already adequately controlled on both inhaled corticosteroid and long-acting beta-2-agonist. Note: Seretide 50/100 microgram strength is not appropriate in adults and children with severe asthma. Chronic Obstructive Pulmonary Disease (COPD) Seretide is indicated for the symptomatic treatment of patients with severe COPD (FEV1 <50% predicted normal) and a history of repeated exacerbations, who have significant symptoms despite regular bronchodilator therapy.

MANUFACTURER

GLAXO SMITHKLINE


Get more information concerning usage, cautions and possible side effects.

MORE DETAILS
Product Details

HOW TO USE THIS PRODUCT:
Seretide Accuhaler is for inhalation use only.

Patients should be made aware that Seretide Accuhaler must be used daily for optimum benefit, even when asymptomatic.

Patients should be regularly reassessed by a doctor, so that the strength of Seretide they are receiving remains optimal and is only changed on medical advice. The dose should be titrated to the lowest dose at which effective control of symptoms is maintained. Where the control of symptoms is maintained with the lowest strength of the combination given twice daily then the next step could include a test of inhaled corticosteroid alone. As an alternative, patients requiring a long acting beta-2-agonist could be titrated to Seretide given once daily if, in the opinion of the prescriber, it would be adequate to maintain disease control. In the event of once daily dosing when the patient has a history of nocturnal symptoms the dose should be given at night and when the patient has a history of mainly day-time symptoms the dose should be given in the morning.

Patients should be given the strength of Seretide containing the appropriate fluticasone propionate dosage for the severity of their disease. Prescribers should be aware that, in patients with asthma, fluticasone propionate is as effective as other inhaled steroids at approximately half the microgram daily dose. For example, 100mcg of fluticasone propionate is approximately equivalent to 200mcg of beclomethasone dipropionate (CFC containing) or budesonide. If an individual patient should require dosages outside the recommended regimen, appropriate doses of beta-agonist and/or corticosteroid should be prescribed.

Recommended Doses:

Asthma

Adults and adolescents 12 years and older:

One inhalation of 50 micrograms salmeterol and 100 micrograms fluticasone propionate twice daily.
or
One inhalation of 50 micrograms salmeterol and 250 micrograms fluticasone propionate twice daily.
or

One inhalation of 50 micrograms salmeterol and 500 micrograms fluticasone propionate twice daily.

Children 4 years and older:

One inhalation of 50 micrograms salmeterol and 100 micrograms fluticasone propionate twice daily.

The maximum licensed dose of fluticasone propionate delivered by Seretide Accuhaler in children 100mcg twice daily.

There are no data available for use of Seretide in children aged under 4 years.

COPD

Adults:

One inhalation of 50 micrograms salmeterol and 500 micrograms fluticasone propionate twice daily.

Special patient groups:

There is no need to adjust the dose in elderly patients or in those with renal impairment. There are no data available for use of Seretide in patients with hepatic impairment.

Using the Accuhaler:

The device is opened and primed by sliding the lever. The mouthpiece is then placed in the mouth and the lips closed round it. The dose can then be inhaled and the device closed.

4.3 Contraindications

Seretide is contraindicated in patients with hypersensitivity (allergy) to any of the active substances or to the excipient. (see 6.1 List of Excipients)

4.4 Special warnings and precautions for use

The management of asthma should normally follow a stepwise programme and patient response should be monitored clinically and by lung function tests.

Seretide Accuhaler should not be used to treat acute asthma symptoms for which a fast and short acting bronchodilator is required. Patients should be advised to have their medicinal product to be used for relief in an acute asthma attack available at all times. Seretide Accuhaler is not intended for the initial management of asthma until the need for and approximate dosage of corticosteroids has been established.

Increasing use of short-acting bronchodilators to relieve symptoms indicates deterioration of control and patients should be reviewed by a physician.

Sudden and progressive deterioration in control of asthma is potentially life threatening and the patient should undergo urgent medical assessment. Consideration should be given to increasing corticosteroid therapy. The patient should also be medically reviewed where the current dosage of Seretide has failed to give adequate control of asthma. For patients with asthma or COPD, consideration should be given to additional corticosteroid therapies.

Treatment with Seretide should not be stopped abruptly in patients with asthma due to risk of exacerbation. Therapy should be down-titrated under physician supervision. For patients with COPD cessation of therapy may also be associated with symptomatic decompensation and should be supervised by a physician.

As with all inhaled medication containing corticosteroids, Seretide should be administered with caution in patients with pulmonary tuberculosis.

Seretide should be administered with caution in patients with severe cardiovascular disorders, including heart rhythm abnormalities, diabetes mellitus, untreated hypokalaemia or thyrotoxicosis.

Potentially serious hypokalaemia may result from systemic beta-2-agonist therapy but following inhalation at therapeutic doses plasma levels of salmeterol are very low.

As with other inhalation therapy paradoxical bronchospasm may occur with an immediate increase in wheezing after dosing. Seretide Accuhaler should be discontinued immediately, the patient assessed and alternative therapy instituted if necessary.

Seretide contains lactose up to 12.5 milligram /dose. This amount does not normally cause problems in lactose intolerant people.

Care should be taken when transferring patients to Seretide therapy, particularly if there is any reason to suppose that adrenal function is impaired from previous systemic steroid therapy.

Systemic effects may occur with any inhaled corticosteroid, particularly at high doses prescribed for long periods. These effects are much less likely to occur than with oral corticosteroids. Possible systemic effects include adrenal suppression, growth retardation in children and adolescents, decrease in bone mineral density, cataract and glaucoma. It is important, therefore, that the patient is reviewed regularly the dose of inhaled corticosteroid is reduced to the lowest dose at which effective control of asthma is maintained.

It is recommended that the height of children receiving prolonged treatment with inhaled corticosteroid is regularly monitored.

Prolonged treatment of patients with high doses of inhaled corticosteroids may result in adrenal suppression and acute adrenal crisis. Children and adolescents lt;16years taking high doses of fluticasone (typically 1000mcg/day) may be at particular risk. Very rare cases of adrenal suppression and acute adrenal crisis have also been described with doses of fluticasone propionate between 500 and less than 1000mcg. Situations, which could potentially trigger acute adrenal crisis in patients, include trauma, surgery, infection or any rapid reduction in dosage. Presenting symptoms are typically vague and may include anorexia, abdominal pain, weight loss, tiredness, headache, nausea, vomiting, hypotension, decreased level of consciousness, hypoglycaemia, and seizures.

Additional systemic corticosteroid cover should be considered during periods of stress or elective surgery.

The benefits of inhaled fluticasone propionate therapy should minimise the need for oral steroids, but patients transferring from oral steroids may remain at risk of impaired adrenal reserve for a considerable time. Patients who have required high dose emergency corticosteroid therapy in the past may also be at risk. This possibility of residual impairment should always be borne in mind in emergency and elective situations likely to produce stress, and appropriate corticosteroid treatment must be considered. The extent of the adrenal impairment may require specialist advice before elective procedures.

Ritonavir can greatly increase the concentration of fluticasone propionate in plasma. Therefore, concomitant use should be avoided, unless the potential benefit to the patient outweighs the risk of systemic corticosteroid side-effects. There is also an increased risk of systemic side effects when combining fluticasone propionate with other potent CYP3A inhibitors (see 4.5 Interaction with Other Medicinal Products and Other Forms of Interaction).

4.5 Interaction with other medicinal products and other forms of Interaction

Both non-selective and selective beta-blockers should be avoided unless there are compelling reasons for their use.

Concomitant use of other beta-adrenergic containing drugs can have a potentially additive effect.

Under normal circumstances, low plasma concentrations of fluticasone propionate are achieved after inhaled dosing, due to extensive first pass metabolism and high systemic clearance mediated by cytochrome P450 3A4 in the gut and liver. Hence, clinically significant drug interactions mediated by fluticasone propionate are unlikely.

In an interaction study in healthy subjects with intranasal fluticasone propionate, ritonavir (a highly potent cytochrome P450 3A4 inhibitor) 100 mg b.i.d. increased the fluticasone propionate plasma concentrations several hundred fold, resulting in markedly reduced serum cortisol concentrations. Information about this interaction is lacking for inhaled fluticasone propionate, but a marked increase in fluticasone propionate plasma levels is expected. Cases of Cushings syndrome and adrenal suppression have been reported. The combination should be avoided unless the benefit outweighs the increased risk of systemic glucocorticoid side-effects.

In a small study in healthy volunteers, the slightly less potent CYP3A inhibitor ketoconazole increased the exposure of fluticasone propionate after a single inhalation by 150. This resulted in a greater reduction of plasma cortisol as compared with fluticasone propionate alone. Co-treatment with other potent CYP3A inhibitors, such as itraconazole, is also expected to increase the systemic fluticasone propionate exposure and the risk of systemic side-effects. Caution is recommended and long-term treatment with such drugs should if possible be avoided.

4.6 Pregnancy and lactation

There are insufficient data on the use of salmeterol and fluticasone propionate during pregnancy and lactation in man to assess the possible harmful effects. In animal studies foetal abnormalities occur after administration of beta-2-adrenoreceptor agonists and glucocorticosteroids (see 5.3 Preclinical Safety Data).

Administration of Seretide to pregnant women should only be considered if the expected benefit to the mother is greater than any possible risk to the foetus.

The lowest effective dose of fluticasone propionate needed to maintain adequate asthma control should be used in the treatment of pregnant women.

There are no data available for human breast milk. Both salmeterol and fluticasone propionate are excreted into breast milk in rats. Administration of Seretide to women who are breastfeeding should only be considered if the expected benefit to the mother is greater than any possible risk to the child.

4.7 Effects on ability to drive and use machines

No studies of the effect on the ability to drive and use machines have been performed

FLIXOTIDE™ ACCUHALER
Fluticasone propionate 50, 100, 250 µg per inhalation
Please read this leaflet carefully before you start taking Flixotide Accuhaler

What is in this leaflet
This leaflet answers some common questions about Flixotide Accuhaler. It does not contain all of the available information.

It does not take the place of talking to your doctor or pharmacist.

All medicines have risks and benefits. Your doctor has weighed the risks of you using Flixotide Accuhaler against the benefits this medicine is expected to have for you.

If you have any concerns about taking this medicine, ask your doctor or pharmacist.

Keep this leaflet with the medicine. You may need to read it again.

What Flixotide Accuhaler is used for
Flixotide Accuhaler contains a medicine called fluticasone propionate. This medicine belongs to a group of medicines known as corticosteroids, frequently called 'steroids'. They are not 'anabolic steroids' which are the steroids sometimes misused by athletes.

Your Flixotide Accuhaler provides a measured amount of steroid for you to breathe into your lungs. By using your Flixotide Accuhaler regularly every day, the medicine reduces the swelling and irritation in the walls of the small air passages in your lungs. Your Flixotide Accuhaler contains the type of asthma medicine known as a 'preventer'. It does not give immediate relief from an asthma attack and may take up to a week to start to work. If your shortness of breath or wheeze does not get better after 7 days, tell your doctor. When used every day, your Flixotide Accuhaler helps to ease breathing problems and prevent asthma attacks.

This medicine is only one part of a general plan to help you manage your asthma. You should discuss this plan with your doctor. You may also be using a 'reliever puffer'. Keep using it according to your doctor's advice. Ask your doctor to check your treatment regularly.

Ask your doctor if you have any questions about why Flixotide Accuhaler has been prescribed for you.

The medicine in Flixotide Accuhaler is not addictive.

Flixotide Accuhaler generally does not cause any problems with your ability to drive a car or operate machinery.

Before you use Flixotide Accuhaler
When you must not use it
Do not use Flixotide Accuhaler if you have ever had an allergic reaction to fluticasone propionate or any of the ingredients listed at the end of this leaflet. See "Side Effects" section for symptoms of an allergic reaction.
Do not use Flixotide Accuhaler if you are pregnant, trying to become pregnant or breastfeeding, unless your doctor says you should. It is important that asthma is managed well during pregnancy and you should not stop your medicine without asking your doctor.
Your doctor will discuss the risks and benefits of using Flixotide Accuhaler if you are pregnant or breastfeeding.
Do not use Flixotide Accuhaler after the expiry date (EXP) printed on the pack.
If you use it after the expiry date has passed, it may not work as well.
Do not use Flixotide Accuhaler if the packaging is torn or shows signs of tampering.
If you're not sure whether you should be using Flixotide Accuhaler, talk to your doctor.

Before you start to use it
You must tell your doctor if:
you are taking other steroid medicines by mouth or inhalation. If you are already taking steroid tablets, you should carry a warning card about needing extra oral steroids during periods of stress. Discuss this with your doctor.
you are taking ritonavir, a medicine used in the treatment of HIV (AIDS)
you have ever had to stop taking other asthma medicines.
you have tuberculosis (TB) of the lung or other long term lung infection.
you are allergic to foods, dyes, preservatives or any other medicines.
Taking other medicines
Tell your doctor if you are taking any other medicines, including medicines you buy without a prescription from a pharmacy, supermarket or health food shop.

Some medicines may affect the way other medicines work. Your doctor or pharmacist will be able to tell you what to do when using Flixotide Accuhaler with other medicines.

Using Flixotide Accuhaler
How to use it
Remember that the medicine in your Flixotide Accuhaler is taken by inhalation only.

You will find the instructions on how to use your Flixotide Accuhaler in the pack. Follow the instructions carefully.

How much to use
The pharmacist's label will usually tell you how many inhalations and how often to use your Flixotide Accuhaler. If you are not sure, ask your doctor or pharmacist.

For adults and children over 16 years of age: The usual dose is in the range of 100 to 1000 micrograms twice daily.

For children over 4 years: The usual dose is in the range of 50 to 200 micrograms twice daily.

Your doctor will decide what dose you should take, how often you should take it, and what strength of Flixotide Accuhaler you should use.

You should visit your doctor or pharmacist regularly to check that you are using your Flixotide Accuhaler in the right way. If you are not breathing the medicine in correctly, the medicine may not be helping you as much as it could.

When not to use it
Do not use your Flixotide Accuhaler to treat a sudden attack of breathlessness. You will need a different kind of medicine called a 'reliever' which your doctor will have told you to take.

How long to use it
You must use your Flixotide Accuhaler every day. Do not stop using it, even if you feel better, unless your doctor tells you.

If you forget to use it
You must use your Flixotide Accuhaler every day. If you forget to take a dose, do not worry. Just take the next dose when it is due.

Do not take a double dose to make up for the dose that you missed.

If you become wheezy or feel tight in the chest before the next dose is due, use a 'reliever puffer' in the usual way. You should get relief from your 'reliever puffer' within a few minutes.

If you have used too much (overdose)
Immediately telephone your doctor or Poisons Information Centre for advice (0800 POISON or 0800 764 766), if you think you may have taken too much of your medicine, even if there are no signs of discomfort or poisoning. You may need urgent medical attention.

Keep telephone numbers for these places handy.

If you are not sure what to do, contact your doctor or pharmacist.

While you are using Flixotide Accuhaler
Things you must do
Tell your doctor or pharmacist that you are using Flixotide Accuhaler if you are about to be started on any new medicines.

If you have to go into hospital for an operation, take your Flixotide Accuhaler with you and tell the doctor what medicine(s) you are taking.

All doctors treating you need to be aware that you are on inhaled steroids. If your body is stressed by, for example, severe infection, surgical operation, an accident etc, you may need steroid tablets or injections for a time.

Tell your doctor if you become pregnant or are trying to become pregnant.

Tell your doctor if, for any reason, you have not taken your medicine exactly as prescribed. Otherwise, your doctor may think that your medicine was not effective and change your treatment unnecessarily.

Things you must not do
Do not stop using Flixotide Accuhaler, or change the dose without first checking with your doctor.

Do not give this medicine to anyone else, even if their symptoms seem similar to yours.

Do not use Flixotide Accuhaler to treat any other complaints unless your doctor says to.

If your Flixotide Accuhaler does not have the usual effect
If your chest condition gets worse, tell your doctor. Your doctor may tell you to take extra puffs of your Flixotide Accuhaler or add another medicine (such as a 'reliever puffer') to your treatment.

IMPORTANT: If your breathing suddenly becomes more difficult just after you have used your Flixotide Accuhaler, you will need to use a 'reliever puffer' and tell your doctor immediately.

Tell your doctor as soon as

possible if:

your 'reliever puffer' does not help your breathing as much as usual
the effect of your 'reliever puffer' does not last as long as usual
you need more puffs of your 'reliever puffer' than usual to get relief.
Side-Effects
Check with your doctor as soon as possible if you have any problems while using Flixotide Accuhaler, even if you do not think the problems are connected with the medicine or are not listed in this leaflet.

Like other medicines, Flixotide Accuhaler can cause some side-effects. If they occur, they are most likely to be minor and temporary. However, some may be serious and need medical attention.

The most commonly reported side-effects are:

a sore throat or tongue. This may be due to 'thrush' (candida infection)
hoarseness or throat irritation
For these, it may be helpful to rinse your mouth with water and spit it out after using your Flixotide Accuhaler. Your doctor may prescribe treatment for the 'thrush' in your mouth while you continue to use your Flixotide Accuhaler.

Very rarely, Flixotide can cause swelling of the throat and face. There may also be an increase in sugar (glucose) in your blood.

Very rarely the person taking the medicine may feel anxious, have disturbed sleep or notice increased irritability (mainly in children).

Taking high doses of steroids for a long time, may affect bone density, or affect the rate of growth in children. It is unclear what, if any, difference this makes to their final height. Taking high doses of steroids for a long time this could affect the adrenal glands, which make the body's own steroid. Your doctor may do tests to check how the adrenal glands are working. Your doctor will be able to answer any questions you may have.

If you feel unwell in any other way or have any symptoms that you do not understand, you should ask your doctor immediately.

Ask your doctor or pharmacist to answer any questions you may have.

If you think you are having an allergic reaction to Flixotide Accuhaler, tell your doctor immediately or go to the Accident and Emergency department at your nearest hospital. Symptoms usually include some or all of the following:

wheezing
swelling of the lips/mouth, face and throat
difficulty in breathing, shortness of breath
hay fever
lumpy rash ("hives")
fainting
This is not a complete list of all possible side-effects. Others may occur in some people and there may be some side-effects not yet known.

Tell your doctor if you notice anything else that is making you feel unwell, even if it is not on this list.

Ask your doctor or pharmacist if you don't understand anything in this list.

Do not be alarmed by this list of possible side-effects. You may not experience any of them.

After using Flixotide Accuhaler
Storage
Keep this medicine where young children cannot reach it.

A locked cupboard at least one-and-a half metres above the ground is a good place to store medicines.

Keep Flixotide Accuhaler in a dry place away from heat (store below 30°C).

Do not leave it in the car or on window sills.

Heat can destroy some medicines.

Disposal
If your doctor tells you to stop using Flixotide Accuhaler, or the product has passed its expiry date, ask your pharmacist what to do with any Flixotide Accuhaler left over.

Product description
What Flixotide Accuhaler looks like.
The Flixotide Accuhaler is a plastic device which contains a foil strip inside. The foil strip has pockets (called blisters) which contain your medicine. The plastic device is labelled, "Flixotide Accuhaler".

Ingredients
Flixotide Accuhaler contains the medicine called fluticasone propionate. It also contains lactose (a milk protein) powder as a non-active ingredient.

Flixotide Accuhaler is available in three strengths:

Flixotide Accuhaler 50 micrograms of fluticasone propionate in a blister
Flixotide Accuhaler 100 micrograms of fluticasone propionate in a blister
Flixotide Accuhaler 250 micrograms of fluticasone propionate in a blister
Each device contains 60 blisters. Your Flixotide Accuhaler has a dose counter which tells you how many doses are left. To let you know when you have reached the last five doses, the numbers appear in red.

Other types of asthma medicines
Your Flixotide Accuhaler contains the kind of asthma medicine known as a 'preventer'. There are other types of inhalers that relieve your breathing problems when you are wheezing or your chest is tight. These medicines are called 'relievers'. Your doctor may tell you to use a 'reliever' in addition to your Flixotide Accuhaler.

Answer 2

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Answer 3

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