What is paramethoxyamphetamine?

Answer 1

PMA is sometimes found in illicit street "Ecstasy" tablets, either alone or in combination with other drugs, and has been associated with numerous adverse reactions including death. Effects of PMA ingestion include many effects of the hallucinogen amphetamines including accelerated and irregular heartbeat, blurred vision, and a strong, reportedly unpleasant feeling of intoxication. There are approximately twice as many deaths caused by PMA as by MDMA, although the actual occurrence of PMA on the market is only a fraction of that of MDMA.

It appears that the drug elevates body temperatures dramatically. Many amphetamines and adrenergic compounds raise body temperatures: whereas some tend to produce more euphoric activity, or peripheral vasoconstriction, or tend to favor one effect over another, it appears that PMA activates the hypothalamus much more strongly than MDMA and other drugs like ephedrine, thereby causing rapid increases in body temperature (which is the major cause of death in PMA mortalities).

Because PMA is given out at the same places that "Ecstasy" tablets are, the risk of being severely injured or hospitalized go up. It is most often sold as "Ecstasy", in the form of tan, beige, or red-colored pills featuring a Mitsubishi logo. [2][3]

Answer 2

PMA for short...
here's an example case, Case2:An 18-year-old man died at his home after ingesting a number of "ecstasy" tablets over five hours, both at a dance club and at home. Two hours after death the core temperature of the body was 39oC. Autopsy revealed focal pericardial haemorrhage, pulmonary congestion and renal tubular necrosis. Toxicological blood analysis showed a lethal level of PMA (1.7 mg/L), with 0.1 mg/L of MDMA and 0.06 mg/L of methylamphetamine. No alcohol was detected in the blood.

most reported fatalities involving the use of 3,4-methylenedioxymethamphetamine (MDMA, or "ecstasy"). In 1998, a series of six cases of death due to an unusual amphetamine drug, paramethoxyamphetamine (PMA), was reported in South Australia

In 1998, our group warned that, although PMA substitution for MDMA appeared at the time to be a local Australian problem, there was a possibility that the manufacture and sale of PMA could occur in other countries. Unfortunately, this prediction has been proved accurate, with recent reports of PMA-related deaths in the United States, Europe and Canada

PMA was created as a contaminant during the synthesis of MDMA and was being disguised and substituted for MDMA by local dealers attempting to offload the drug.1,6,7 However, this is now considered unlikely, as the chemical precursors of PMA and MDMA are different, and information received concerning Case 3 (described here) suggests that capsules containing only PMA are being marketed specifically to augment the effects of MDMA. This is an extremely dangerous development, as it is well recognised that PMA has a much greater propensity to produce adverse effects than other ring-derivative amphetamines.

Answer 3

Para-methoxyamphetamine

Answer 4

Paramethoxyamphetamine, or PMA, is a hallucinogen/psychostimulant. It is often an ingredient in illicit "Ecstasy" pills. It is EXTREMELY dangerous.

Answer 5

Paramethoxyamphetamine, 4-MA, 4-methoxyamphetamine, C10H15NO (mol. wt. 165.23)


A strong stimulant, toxic, sometimes found in or represented as ecstasy

Answer 6

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What is paramethoxyamphetamine?