how does vitamin K effect warfarin?

Answer 1

Warfarin is a blood thinner and Vitamin K is needed for proper blood clotting (coagulation). When you're on Warfarin, you shouldn't eat too much Vitamin K because it can interfere with the ability of the Warfarin to do it's job. Vitamin k could be found mainly in greens.

Answer 2

Warfarin is a vitamin K antagonist. If there is an overdose of Warfarin, vitamin K is given to prevent bleeding.

Answer 3

Vitamin K is considered the "antidote" for warfarin/Coumadin. As you may know (if you're asking this question), warfarin slows clot aggregation by interferring with vitamin k - dependent clotting factors. When given as an antidote - vitamin k acts to stimulate production of more clotting factors

Vitamin K is a fat soulable vitamin, normally synthesized by the bacteria in our intestines and eaten in foods such as: "cabbage, cauliflower, spinach and other green leafy vegetables, cereals, soybeans, and other vegetables." The bloods ability to clot is dependent upon vitamin k.

There are a series of clotting factors (II, VII, IX, X) that are synthesized only with sufficient levels of vitamin K. When taken, warfarin interfers with the production of these clotting factors thus effectivelly slowing the clotting potential of the blood, or you may have refered to it as "thinning" the blood.

If warfarin is taken in excess it is apperant on the patient's lab tests (PT/PTT and INR) and vitamin k will be administered. The health team wants a therapeutic level of the warfarin.

phytonadione (Vitamin K) - is administered normally (in my experience) to two sets of patients. Wafarin overdoses and newborn babies (all newborns have sterile bowels and are not producing vitamin K and subsequent dependent clotting factors - risk for bleeding)

For warfarin overdose/ and management vitamin k is administered:
Adults: 2.5-10mg subcutaneously based on prothrombin time and international normalized ratio. May repeat 6-8hrs PRN (as needed)
In an emergency: 2.5-25mg slow IV infusion may repeat 6-8 hrs after first dose


I hope this answers you question. By the way if you are taking Coumadin/warfarin, consult your doctor before consuming excess food products containing vitamin k, this may effectively alter the therapeutic level of the Comadin and may be dangourous to you health. Please consult with your primary health provider for further assistance.

Answer 4

This is given via injection, or mouth to reverse the blood thinning effects that Warfarin (Coumadin) has on the blood. You should not be on both at the same time.