Pus is a whitish-yellow or yellow substance produced during inflammatory responses of the body that can be found in regions of pyogenic bacterial infections. An accumulation of pus in an enclosed tissue space is known as an abscess. A visible collection of pus within or beneath the epidermis, on the other hand, is known as a pustule or pimple. Pus is produced from the dead and living white blood cells which travel into the intercellular spaces around the affected cells.
Pus consists of a thin, protein-rich fluid, known as liquor puris, and dead neutrophils, which are part of the body's innate immune response. Neutrophils are produced in the bone marrow and released into the blood. When the need to fight infection arises, they move to the site of infection by a process known as chemotaxis, usually triggered by cytokine release from macrophages that sense invading organisms. At the site of infection they engulf and kill bacteria. After it has killed a bacterium, the neutrophil dies. These dead cells are then phagocytosed by macrophages, which break them down further. Pus, therefore, is the creamy material composed of these dead neutrophils.
Neutrophils are the most abundant type of leukocyte in human blood, comprising anywhere between 40% to 75% of leukocytes.
2007-02-14 01:43:33
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answer #2
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answered by Anonymous
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