Please help me with this question. Hispanic families have a much lower rate of autism, I expect that they complete their families when the father is substantially younger and therefore have much fewer age related mutations in sperm. The risk of autism has been related to the increased age of the fathers in non-familial cases. Thank you for your knowledge, this is important!
2007-02-08
14:13:57
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3 answers
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asked by
Alex
2
in
Family & Relationships
➔ Family
http://www.washingtonpost.com/wp-dyn/content/article/2006/05/04/AR2006050401724.html
2007-02-08
14:14:31 ·
update #1
There have been many studies that link older paternal age and autism. The CDC is not interested in presenting this evidence for some reason. here is one link, please read it carefully. http://www.schizophreniaforum.org/for/curr/Malaspina/default.asp
2007-02-09
06:42:58 ·
update #2
It is fine if you don't want to accept the older father explanation as a risk factor for for non-familial autism. It is certainly up to you. http://www.intelihealth.com/IH/ihtIH/WSIHW000/35320/63153/491833.html?d=dmtHMSContent
2007-02-09
07:42:22 ·
update #3
I am wondering what you think is the cause of autism?
2007-02-09
07:57:28 ·
update #4
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16108999&dopt=Abstract
2007-02-09
08:10:11 ·
update #5
Chickenboxer I don't think you read the paper on the Male Germ Line thoroughly from what you said. There are many pieces missing from understanding exactly what happens to sperm as men age and this research is not getting funding.
http://www.sciencedaily.com/releases/2002/10/021018080014.htm
http://www.sciencedaily.com/releases/2002/11/021126201311.htm
http://www.pnas.org/cgi/content/full/94/16/8380
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=6927656&query_hl=2&itool=pubmed_docsum
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed
If a 50 year old man asked you from your reading of the research on autism if you thought he'd would have the same risk of fathering an autistic child as a 24 year old with no family history of autism. What would you say to him?
2007-02-09
08:40:08 ·
update #6
All genetic illnesses have their origin in a distant or recent mutation. Paternal age is an important determinant of mutation frequency in new germ cell mutation, causing both autosomal dominant and X-linked recessive illnesses. The role of other mutagenic factors is not the subject of this study. The results of my own research are supported by other information which indicates that the leading cause of genetic illness present in human populations is the ageing process in the male. Conceiving children by men younger than 35 years of age would prevent many genetic illnesses in future generations.
Leslie B.Raschka, M.D. Age of the Father and the Health of Future Generations
2007-02-09
08:51:26 ·
update #7
They said it was important to understand the effects of men having children at ever-older ages.
"Since 1980 there has been about a 40 percent increase in 35- to 49-year-old men fathering children, and a 20 percent decrease in fathers under 30," they wrote.
Andrew Wyrobek's study June 2006
2007-02-11
08:36:18 ·
update #8