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Please help me with this question. Hispanic families have a much lower rate of autism, I expect that they complete their families when the father is substantially younger and therefore have much fewer age related mutations in sperm. The risk of autism has been related to the increased age of the fathers in non-familial cases. Thank you for your knowledge, this is important!

2007-02-08 14:13:57 · 3 answers · asked by Alex 2 in Family & Relationships Family

http://www.washingtonpost.com/wp-dyn/content/article/2006/05/04/AR2006050401724.html

2007-02-08 14:14:31 · update #1

There have been many studies that link older paternal age and autism. The CDC is not interested in presenting this evidence for some reason. here is one link, please read it carefully. http://www.schizophreniaforum.org/for/curr/Malaspina/default.asp

2007-02-09 06:42:58 · update #2

It is fine if you don't want to accept the older father explanation as a risk factor for for non-familial autism. It is certainly up to you. http://www.intelihealth.com/IH/ihtIH/WSIHW000/35320/63153/491833.html?d=dmtHMSContent

2007-02-09 07:42:22 · update #3

I am wondering what you think is the cause of autism?

2007-02-09 07:57:28 · update #4

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16108999&dopt=Abstract

2007-02-09 08:10:11 · update #5

Chickenboxer I don't think you read the paper on the Male Germ Line thoroughly from what you said. There are many pieces missing from understanding exactly what happens to sperm as men age and this research is not getting funding.
http://www.sciencedaily.com/releases/2002/10/021018080014.htm

http://www.sciencedaily.com/releases/2002/11/021126201311.htm

http://www.pnas.org/cgi/content/full/94/16/8380

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=6927656&query_hl=2&itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed

If a 50 year old man asked you from your reading of the research on autism if you thought he'd would have the same risk of fathering an autistic child as a 24 year old with no family history of autism. What would you say to him?

2007-02-09 08:40:08 · update #6

All genetic illnesses have their origin in a distant or recent mutation. Paternal age is an important determinant of mutation frequency in new germ cell mutation, causing both autosomal dominant and X-linked recessive illnesses. The role of other mutagenic factors is not the subject of this study. The results of my own research are supported by other information which indicates that the leading cause of genetic illness present in human populations is the ageing process in the male. Conceiving children by men younger than 35 years of age would prevent many genetic illnesses in future generations.
 
Leslie B.Raschka, M.D. Age of the Father and the Health of Future Generations

2007-02-09 08:51:26 · update #7

They said it was important to understand the effects of men having children at ever-older ages.

"Since 1980 there has been about a 40 percent increase in 35- to 49-year-old men fathering children, and a 20 percent decrease in fathers under 30," they wrote.

Andrew Wyrobek's study June 2006

2007-02-11 08:36:18 · update #8

3 answers

Fatherless America! thundered the title of a provocative book, followed by the subtitle’s pressing tone: Confronting Our Most Urgent Social Problem.[i] The most urgent social problem in the United States today, according to some scholars, is the increasing number of fathers who either are not in the home or are ineffective parents while at home.

A variety of studies, publications, and social programs in recent years have focused attention on the issue of fathering.

2007-02-13 02:36:16 · answer #1 · answered by Sweet n Sour 7 · 0 0

Please don't take this as a bash because it isn't. It seems to me that you are not understanding the scientific facts. Your link says nothing about mutated sperm or Hispanic father's age-could you provide a link that does? Is there any scientific study that shows this? It does mention the fact that there are fewer diagnoses within the Hispanic population. You missed the part where experts say it is due to lack of medical resources which makes a lot of sense since an overwhelming majority of Hispanics do not have health care. Your link does try the old mercury causation argument, however and cites the work of the Giers which has been proven to be grossly false and as a result, they have lost all of their credibility within the scientific community.
I'm not trying to offend but you don't have your facts straight and it could confuse a lot of people.

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Your link cites one study whose main focus was on schizophrenia. The results for autism were limited since this was not the scope for study. it indicates that the data seemed to support a hypothesis but this hypothesis was about neruological disorders in general-not autism specifically. And while it may support much of their hypothesis, it is still that-a hypothesis. Until it reaches the realm of scientific theory, it doesn't have much weight and should not be construed as being accepted within the medical community (which it is not). Just because two things may show a corelation (age of father and incidence of nuerologically impaired offspring), it does not equal causation (autism).

Again, I'm not trying to bash you but I know people read things, accept them as fact, and as a result, bad information spreads and impacts real people like me-a parent of a child on the autistic spectrum. Until things are proven and accepted within the scientific and medical community, it is wrong to report it as fact. This happened with the mercury-vaccine hypothesis which has been disproven time and time again, yet misinformation is all over the place and has a lot of parents confused. Again, I ask you to please show me a peer reviewed (which means that other scientists in the field agree with the results, testing procedures, ect) study showing a link between mutated sperm and autism. Here's a hint-there isn't one.

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Verbatim (below) from your most recent link. Here's the kicker they admit fallacies in their testing:


This study has important implications for what causes autism, but it also has limitations:

The researchers did not have specific information about the severity of mental retardation or language ability.


It's possible that the autistic traits arose as the father aged, but were passed on because they were part of the fathers' genetic make-up all along.


Maybe people with autistic traits are more likely to become fathers later in life, slanting the data.


Older fathers could have passed along genes for other psychiatric disorders that have traits that look like autism.


The researchers did not have access to information about the child's birth environment or development.



In other words, it's a cop out for any critisism or contrary research. These omissions of critical data are kind of important, don't you think? Junk Science is what I'd call it.

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I believe it is genetic as your latest link from PubMed (which is a good source) states. It is the only theory that holds with most of the scientific and medical communities. It mentions nothing of mutated sperm due to older age, however which was the crux of your argument originally. I'm not saying that one day there won't be evidence of this but as of now there isn't. I don't want others to read your question and think this hypothesis has many believers that are in the field of autism research because it doesn't. That may or may not change in the future but hasn't shown causation to date.


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You are spitting out links that have nothing to do with autism specifically. You have now strayed WAY off your original question in which you conclude
a)Hispanic families have a lower rate of autism

and

b)That age related mutations in sperm cause autism.

You have not been able to prove either point. In fact, you have abandoned it altogether and just want to throw a bunch of articles (some questionable) out there that show corelation between neurological disorders and mutated sperm. I never said I don't think it may be the cause for some other disorders BUT NOT AUTISM.

Also, I would tell the middle aged fellow to do his research and come to his own conclusions. I wouldn't advise him trust shady studies like the ones you have provided.

That is all. We'll just agree to disagree.

2007-02-09 14:14:25 · answer #2 · answered by chikkenbone 3 · 0 0

Why wouldn't they?

2007-02-15 17:39:16 · answer #3 · answered by ferrariman610 2 · 0 0

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