If a patient is prescribed odansetron 8mg orally, and tablets are not available, can we use the intravenous liquid orally? If the patient receives an oral dose in the morning, and an IV dose later on in the evening, can there be a doubling-up effect as the delayed absorbtion of the morning oral dose catches up with the rapidly absorbed IV dose?
2007-02-06 10:40:19 · 3 answers · asked by Anonymous in Science & Mathematics ➔ Medicine
Ask the hospital pharmacist. The bio-availability of an IV formulation may be poor when given orally. It may not be properly absorbed, it may not be absorbed in a bio-effective form or it may have a large First Pass effect (cleared in the liver before leaving the portal circulation to the rest of the body.
The PDR may not include this data.
2007-02-06 12:48:26 · answer #1 · answered by dreamlessleep 3 · 1⤊ 0⤋
i'm not a doctor but i can guess that the iv liquid is more concentrated than an oral medication so i wouldn't take it orally.
2007-02-06 11:16:40 · answer #2 · answered by iwuvmyhubby 2 · 0⤊ 0⤋
I wouldn't do anything without an order from the prescribing MD....call down to the Pharmacy and see what they say. I'll bet that they will tell you no.
2007-02-06 11:50:37 · answer #3 · answered by Anonymous · 1⤊ 0⤋
i don tink so that IV Zofran can be used orally....it's best to consult a doctor esp when IV solutions is concerned...
2007-02-06 18:13:56 · answer #4 · answered by jas 2 · 1⤊ 0⤋