what's the difference between Myasthenia Gravis and Curare?

Question

they both block acetylocholine receptors dont they?

Answer 1

Myasthenia gravis is a disease and curare is a medication.

Answer 2

I can understand your confusion. They both result in paralysis for "similar" reasons, and eventual death if left untreated. But Myasthenia Gravis is an autoimmune disease; the immune system creates antibodies against ACh receptors. If ACh cannot bind to the receptors at the NMJ, no action potential is created, thus no muscle contraction. So yes, ACh receptors are "blocked," but they are actually destroyed.

Curare is an antagonist. It binds to the ACh receptors, thus ACh cannot bind. So again, no action potential to muscle fibers and no contraction. No destruction of receptors with Curare.

Answer 3

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