What is Dopram-V?

Question

i know vets use it, but what does it do to the animals, why do they give it to them and when do they give it to them.

Answer 1

Dorpram-V is the veterinary form of doxapram. Doxapram stimulates respiration (breathing) and is used after a difficult birth, or after general anesthesia. Please see the references below for detailed information.

Answer 2

Dopram-V (doxapram) belongs to a group of drugs called analeptics. They stimulate chemoreceptors in the carotid arteries, which in turn, stimulates the respiratory center in the brain stem. In humans doxapram is used in intensive care settings to stimulate the respiratory rate in patients with respiratory failure. It is also used in opioid overdose (heroin, oxycodone etc.) to overcome respiratory depression, the primary cause of death with these drugs.

In animals it is used for the same reasons as in humans. Doxapram stimulates the medullary respiratory center and the chemoreceptors of the carotid artery and aorta to increase tidal volume. Other portions of the CNS are stimulated only when high doses are administered. Doxapram is primarily used in emergency situations during anesthesia or to decrease the respiratory depressant effects of opiates/opioids and barbiturates. Recommended dosages are 1-5 mg/kg, IV, in dogs and cats, or 1-2 drops under the tongue of apneic neonates (newborns). In adult horses, the dosage is 0.5-1.0 mg/kg, IV, while foals are dosed carefully at 0.02-0.05 mg/kg/min, IV.

Hope this helps.

Rick the Pharmacist