Is the mutation frequency of adult WBC different from liver or skeletal muscle,why and how?

Question

Assuming the most mutations are introduced during replication,would you expact the mutation frequency of an adult WBC to be different from those of the liver or skeletal muscle.

Answer 1

The answer to your question is yes. Liver and muscle cells normally do not replicate unless there is some form of need like injury. WBC on the other hand normally has a lifespan and so it is constantly replaced by the body. In theory, the faster a cell replicates, the more chance it has that there will be errors that occur during its replication and in your scenario, the more chances that mutation can occur. Mutation does not occur as easily as it sounds and is influenced aby a lot of factors. The human body has a very good way of policing itself against things like mutation.