2007-01-27 20:57:14 · 4 answers · asked by M sha 1 in Science & Mathematics ➔ Medicine
Medical application of radio isotops for:
A-Diagnosis (using radiocative traces)--> no pharmacological action , used in a low dose and short half lives
B-Treatment or theraputic(using radioactive sources)-->have a pharmacological action, used in a high dose and long half life
A-For diagnosis:
1-Isotop dilution technique(tech.)->for measuring Blood volume by useing RADIO IODINATED HUMAN SERUM ALBUMIN
2-Isotop disappearance tech.->for measure half life of RBCs in case of hemolytic animea by using Cr51
#Normal RBC half life (30-33 days) but hemolytic (1-7days)
3-Isotop trnasfer rate tech.-> for determination the circulation time by using Na24
4-Isotop uptake tech.->for determination the function of the vital organs such as:
-Thyroid (using oral NaI131 )
-Liver (using i.v. rose bengal with I131)
-Renal function (using i.v. of rose bengal with I131 or iodohippurate with I131)
5-Scanning techn.-> for scanning organs
-as in uptake tech redioactive isotops for organs
+ RBCs labeled by Cr51 for scanning of SPLEEN
B-Theraputic application:
1-External radiation source:-
-Teletherapy source(Co60 and Cs137 for treatment(ttt) of lesions)
-Surface source(P32 and Sr90 for ttt bladder tumors
-Extracorporea irridiation source(Co60 and Y90 for irridiate blood to prevent the rejection of grafts)
2-Internal radiation source:-
-Implanted source(Co60 and Cs137 used interstital implants for ttt of certain tumors
-Locally injected source(# P32 injected intraperitoneally after surgical removal of ovarian cancer to kill any other cancerous cells and # Au198 and Y90 injected intra-articularly for ttt inflammed joints
-Selectively concentrated (conc.)source(# P32 selectively conc. in bones for ttt of exssive Erythrogenesis (polycythemia) and # I131 for ttt of hyperthyrodism
2007-01-31 07:01:54 · answer #1 · answered by Anonymous · 0⤊ 0⤋
Radioactive isotopes inn on an identical organs as non radioactive factors.Their concentration in organs and tissues may well be measured. This learn has the two diagnostic and healing fee. Thorium mapping of heart demarcates areas in heart receiving adequate blood as against areas no longer receiving it.. this concepts is extra sensible than an angiogram. Angiogram can say a block in blood vessels exists or no longer yet Thorium mapping tells no depend if the block is compensated by utilising organic bypass of collateral vessels. Radioactive iodine gets concentrated in Thyroid proportionate to the pastime of the gland. Hyperthyroid gland ascini additionally are destroyed by utilising radioactive iodine. Metabolism of any factor ,compound or drug may well be accompanied up interior the physique by utilising making one factor of the compound radioactive.
2016-11-01 11:54:57 · answer #2 · answered by ? 4 · 0⤊ 0⤋
Radio isotopes are simply forms of elements that emit radiation. Usually, pharmaceutical researchers tag hydrogen in their drugs because it is abundent (it is in every cell of the body), it decays harmlessly by emitting alpha particles and can show where the drug acculates and how long it can stay in the body.
Radioactive iodine, is commonly used to slow down the thyroid (it will desroy thyroid cells) because the thyroid collects iodine more than any other body system. This is common treatment for hyperthyroidism. Also, non-radioactive iodine is sold as anti-radiation pills because the thyroid will saturate with the safe iodine and not accumulate radioactive iodine, which is found in fallout and uraniam decay.
Radioactive thorium is used in cardiac stress-tests for similar reasons.
2007-01-27 22:24:18 · answer #3 · answered by Matthew P 4 · 0⤊ 0⤋
Just answered.
2007-01-27 21:04:27 · answer #4 · answered by J.SWAMY I ఇ జ స్వామి 7 · 0⤊ 0⤋