Have you heard of Hurier's syndrome?

Answer 1

Do you mean Hurler's syndrome? I don't know of a simple way to explain it. It's a rare recessive inherited disorder. (The inherited trait comes from both mother and father.) Affected children may appear normal at birth, but then develop coarse features, cloudy corneas, thick gums, enlarged liver and spleen, abnormal vertebral development, plus other signs and symptoms including mental retardation. A family with one affected child is at risk for having other affected children. They should be given the option to seek genetic counseling. Treatment includes bone marrow transplantation, enzyme replacement therapy and gene therapy, all of which have had limited success. More recently, stem cells from cord blood have shown promise. Early diagnosis is key. Major pediatric medical centers may have specialty clinics treating Hurler syndrome and related disorders.

Answer 2

I couldn't find anything on Hurier's. Did you mean Hurler's by any chance?

http://www.nlm.nih.gov/medlineplus/ency/article/001204.htm