grapefruit reduces the absorption rate of some medications
grapefruit juice (unlike any other citrus juice) inhibits two enzymes that are important in metabolizing, or breaking down, these medications. When the enzymes aren't doing their job, much more of the drug in question remains available to enter the patient's bloodstream, and in some cases, this can have dangerous, even toxic, effects.
2007-01-11 04:06:40
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answer #1
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answered by Anonymous
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CANDY,
Any number of medications can apply to this question: Prozac, BuSpar, Tegretol, Lipitor, Verapamil, Prednisone and a host of others - even Viagra!
A. The reason why grapefruit juice is a problem for people taking certain drugs - including many psychotropic meds - is that grapefruit juice (unlike any other citrus juice) inhibits two enzymes that are important in metabolizing, or breaking down, these medications. When the enzymes aren't doing their job, much more of the drug in question remains available to enter the patient's bloodstream, and in some cases, this can have dangerous, even toxic, effects.
For example, as much as 99% of BuSpar (Buspirone) is normally metabolized before the drug ever enters the bloodstream. When taken in the presence of grapefruit juice (not even at the same time), the amount of BuSpar in the system could increase as much as 400% - a hazardous situation.
2007-01-11 05:53:14
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answer #2
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answered by Dr. Albert, DDS, (USA) 7
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This primarily applies to grapefruit juice not grapefruit. Since the juice interferes with the Cytochrome P-450 enzyme system, you should avoid the concurrent use of Valium and grapefruit juice unless you want a more sustained and higher effect from the Valium.
2007-01-11 04:41:43
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answer #3
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answered by Yaounde A 1
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How should I take Valium?
Take Valium exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Valium may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death. Selling or giving away this medicine is against the law.
Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
Valium should be used for only a short time. Do not take this medicine for longer than 4 months without your doctor's advice.
Do not stop using Valium suddenly, or you could have increased seizures or unpleasant withdrawal symptoms. Ask your doctor how to safely stop using diazepam.
Call your doctor at once if you feel that this medicine is not working as well as usual, or if you think you need to use more than usual.
While using Valium, you may need frequent blood tests at your doctor's office.
Store at room temperature away from moisture, heat, and light. After you have stopped using this medicine, flush any unused pills down the toilet.
Keep track of the amount of medicine used from each new bottle. Valium is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
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2016-05-27 13:44:14
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answer #4
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answered by Anonymous
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grapefruit chemically reacts with the valium to turn it into lycit acid which destroys your liver and causes heart popultations. drinking enhances the valium which means twice the affect. This can be bad because taking too much can kill you and if you double the effect it's hard to "regulate" how much your body can hadle...
2007-01-11 04:07:19
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answer #5
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answered by b4freedom 3
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The enzimes in a grapefruit has an adverse effect with the valuim thus destroying the liver
2007-01-11 05:28:53
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answer #6
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answered by a_word_of_praise 2
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The enzymes in grapefruit react adversely or impact the efficacy of several types of medicine. Check w/ your pharmacist.
2007-01-11 04:06:50
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answer #7
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answered by bandit 6
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Because it metabolizes into cyanide upon contact to human immune systems. Trust me on that one.
2007-01-11 04:07:08
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answer #8
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answered by Harsh Noise Wall 4
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it interferes with the metabolization of several medications
2007-01-11 06:48:27
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answer #9
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answered by shiara_blade 6
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BEER
2007-01-11 04:06:10
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answer #10
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answered by Anonymous
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