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tabes dorsalis

Tabes dorsalis is a slow degeneration of the nerve cells and nerve fibers that carry sensory information to the brain. The degenerating nerves are in the dorsal columns of the spinal cord (the portion closest to the back of the body) and carry information that help maintain a person's sense of position.

Cause
Tabes dorsalis is the result of an untreated syphilis infection.

Symptoms
Symptoms may not appear for some decades after the initial infection and include weakness, diminished reflexes, unsteady gait (locomotor ataxia), progressive degeneration of the joints, loss of coordination, episodes of intense pain and disturbed sensation inclusive glossodynia, personality changes, dementia, deafness, visual impairment, and impaired response to light.

Prognosis
If left untreated, tabes dorsalis can lead to paralysis, dementia, and blindness. Existing nerve damage cannot be reversed.

Incidence/Prevalence
The disease is more frequent in males than in females. Onset is commonly during mid-life. The incidence of tabes dorsalis is rising, in part due to co-associated HIV infection.

Treatment
Penicillin, administered intravenously, is the treatment of choice. Associated pain can be treated with opiates, valproate, or carbamazepine. Patients may also require physical or rehabilitative therapy to deal with muscle wasting and weakness. Preventive treatment for those who come into sexual contact with an individual with tabes dorsalis is important.

2007-01-06 15:22:56 · answer #1 · answered by crowfeathers 6 · 0 0

You probably mean tabes dorsalis.
These are syphillis terminology of symptoms found in the patients during the pre penicillin therapy era.
They hardly mention it these days since syphillis is largely treated in stage s 2 and 3 already.
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also called Progressive Locomotor Ataxia, rare neurologic form of tertiary syphilis, involving sensory deficits, loss of neuromuscular coordination, and diminished reflexes. Symptoms of this form of neurosyphilis chiefly affect the legs and may not appear for more than 25 years after the initial infection. Untreated, tabes dorsalis usually makes unassisted walking impossible and severely debilitates the victim.
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I guess you may still run into older undiagnosed untreated (25 yrs+) adults with the said symptoms.

2007-01-06 15:37:19 · answer #2 · answered by QuiteNewHere 7 · 0 0

neurospyphilis.

2007-01-06 15:19:53 · answer #3 · answered by cece 4 · 0 0

its called tuberculosis--don't get it

2007-01-06 15:14:01 · answer #4 · answered by Anonymous · 0 1

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