There are two main types of lung cancer categorized by the size and appearance of the malignant cells seen by a histopathologist under a microscope: non-small cell (80%) and small-cell (roughly 20%) lung cancer. This classification although based on simple pathomorphological criteria has very important implications for clinical management and prognosis of the disease.
Non-small cell lung cancer
The non-small cell lung cancers (NSCLC) are grouped together because their prognosis and management is roughly identical. When it cannot be subtyped, it is frequently coded to 8046/3. The subtypes are:
(M8070/3) Squamous cell carcinoma, accounting for 20% to 25% of NSCLC, also starts in the larger breathing tubes but grows slower meaning that the size of these tumours varies on diagnosis.
(M8140/3) Adenocarcinoma is the most common subtype of NSCLC, accounting for 50% to 60% of NSCLC. It is a form which starts near the gas-exchanging surface of the lung. Most cases of the adenocarcinoma are associated with smoking. However, among non-smokers and in particular female non-smokers, adenocarcinoma is the most common form of lung cancer. A subtype of adenocarcinoma, the bronchioalveolar carcinoma, is more common in female non-smokers and may have different responses to treatment.
Large cell carcinoma is a fast-growing form that grows near the surface of the lung. It is primarily a diagnosis of exclusion, and when more investigation is done, it is usually reclassified to squamous cell carcinoma or adenocarcinoma.
Small cell lung cancer
Lung small cell carcinoma (microscopic view from a core needle biopsy)(M8041/3) Small cell carcinoma (SCLC, also called "oat cell carcinoma") is the less common form of lung cancer. It tends to start in the larger breathing tubes and grows rapidly becoming quite large. The oncogene most commonly involved is L-myc. The "oat" cell contains dense neurosecretory granules which give this an endocrine/paraneoplastic syndrome association. It is initially more sensitive to chemotherapy, but ultimately carries a worse prognosis and is often metastatic at presentation. This type of lung cancer is strongly associated with smoking.
Other types
Carcinoid
Adenoid cystic carcinoma
Cylindroma
Mucoepidermoid carcinoma
Metastatic
The lung is a common place for metastasis from tumors in other parts of the body. These cancers, however, are identified by the site of origin, i.e., a breast cancer metastasis to the lung is still known as breast cancer. The adrenal glands, liver, brain, and bone are the most common sites of metastasis from primary lung cancer itself.
2007-01-06 03:42:41
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answer #1
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answered by memo 3
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Squamous cell cancer--it means "scalelike" . It is usually a cancer of the flat epithelial cells lining the lungs. Depending on staging, and speed of diagnosis, prognosis varies.
2007-01-06 03:50:23
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answer #2
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answered by Queen-o-the-Damned 3
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Lung cancer is the most comon cause of cancer related death in both men and women. there are two general types of lung cancer small cell and non small cell, small cell cancer grows fastest.
Lung cancer can cause a persistent cough, sputum with blood, chest pain ,shortness of breath ,fatigue, hoarseness, weight loss, loss of appetite, resurring bronchitis or pneumonia, fever for an undnown reason, wheezing, swelling of neck and face.
2007-01-06 04:38:13
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answer #3
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answered by picture 1
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Squamous cell- it's a type of non-small cell lung cancer.
2007-01-06 03:42:26
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answer #4
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answered by Cyndi S 2
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squamous--it is a slow growing cancer that starts in the large breathing tubes they are thin flat cellsthat look like fish scales...
2007-01-06 07:31:47
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answer #5
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answered by Anonymous
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adenoid
2017-02-18 11:06:51
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answer #6
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answered by Sue 1
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I believe you are referring to squamous cell carcinoma.
2007-01-06 03:42:30
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answer #7
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answered by Anonymous
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