THE CORRECT ANSWER IS DENTSTS DON'T USE IT ANYMORE.
DENTISTS NORMALLY USE LIDOCAINE OR MEPIVACAINE INSTEAD OF PROCAINE (NOVACAINE), THE RESULTS FOR DENTAL WORK IS BETTER FOR THE FORMER CHEMICALS.
Procaine
From Wikipedia, the free encyclopedia
(Redirected from Novocaine)
Jump to: navigation, search
For other uses of the name Novocaine and other spellings thereof, see Novocaine (disambiguation).
Procaine
Systematic (IUPAC) name
2-(diethylamino)ethyl 4-aminobenzoate
Identifiers
CAS number 59-46-1
ATC code N01BA02 C05AD05 S01HA05
PubChem 4914
DrugBank APRD00650
Chemical data
Formula C13H20N2O2
Mol. weight 236.31
Pharmacokinetic data
Bioavailability n/a
Metabolism hydrolysis by plasma esterases
Half life 40–84 seconds
Excretion renal
Therapeutic considerations
Pregnancy cat. B2 (Australia)
C (U.S.)
Legal status Schedule 4 (Australia)
Routes parenteral
Procaine is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and is also used in dentistry. Owing to the ubiquity of the trade name Novocain, procaine is sometimes referred to generically as novocaine or novacaine.
Procaine was first synthesized in 1905, and was the first injectable man-made local anesthetic used. It was created by the German chemist Albert Einhorn (1857-1917) who gave the chemical the trade name Novocaine, from the Latin Novus (meaning New) and caine, as in "cocaine." It was introduced into medical use by surgeon Heinrich Braun (1862-1934).
Procaine is rarely used today since more effective (and hypoallergenic) alternatives such as lidocaine (xylocaine) exist. Prior to the discovery of procaine, cocaine was the most commonly used local anesthetic. Procaine (like cocaine) has the advantage of constricting blood vessels, which reduces bleeding, unlike other local anesthetics like lidocaine, and without the euphoric and addictive qualities of cocaine.
Procaine, an ester anesthetic, is metabolized in the plasma by the enzyme pseudocholinesterase through hydrolysis into para-amino benzoic acid (PABA), which is then excreted by the kidneys into the urine. Allergic reactions to procaine are usually not in response to procaine itself, but to PABA. About 1 in 3000 people have an atypical form of pseudocholinesterase, which doesn't hydrolyze ester anesthetics such as procaine, resulting in a prolonged period of high levels of the anesthetic in the blood and increased toxicity.
Procaine is the primary ingredient in the controversial preparation Gerovital H3, which is claimed by its advocates to remedy many effects of aging. The mainstream medical view is that these claims were seriously studied and discredited in the 1960s.
2007-01-03 14:07:58
·
answer #1
·
answered by Dr. Albert, DDS, (USA) 7
·
1⤊
0⤋
This can be confusing. You have mostly correct answers above, but what has been left out is that "novacaine" has become the sort of generic term for anything that a dentist injects to get you numb. Nobody has used actual "Novacaine" since the early 1960's, but since it used to be the only chemical available, the name stuck in common usage. Not everyone tissue is a Kleenex, but many people use that name for all tissues. "Anyone have a Kleenex?"
Dentists probably could not practice without using some kind of injectable local anesthetic solution - many have been named above - but we have not used actual Novacaine since sometime before I became a dentist.
2007-01-03 17:19:39
·
answer #2
·
answered by Jess 5
·
2⤊
0⤋
Most dentists use either septocaine, lidocaine, or if high blood pressure or other heart issues, they use mepivicaine. All are related to novacaine. And for those of you who received nothing, most likely didn't need it, I've had three fillings and only was numbed for one of them. If the decay doesn't get that close to the nerve then you won't feel pain, just slight sensitivity.
2007-01-03 14:05:37
·
answer #3
·
answered by pollyzmama 3
·
1⤊
0⤋
My dentist did around july 2006 to pull my wisom teeth.
Yep thats right I was awake the whole procedure.
I had no complications either and everything healed up nicely.
But he told me it was novacaine so Im sure of it and I read my medical record so it was confirmed.
2007-01-04 01:02:50
·
answer #4
·
answered by mayreeha84 1
·
0⤊
0⤋
Most dentists don't anymore. Some still do. My dentist didn't use anything to numb my teeth during a filling!
2007-01-03 13:46:43
·
answer #5
·
answered by artwizs 3
·
0⤊
1⤋
Yes, this is true. No Dentists use it anymore, at least ones that value their License. They dont even make it anymore.
They use Xylocaine, Lidocaine, Marcaine, Carbocaine, Septocaine, Polocaine.
The type used depends on the the procedure the length of time needed and the patients health history. Hope this helps, take care.
2007-01-03 13:47:49
·
answer #6
·
answered by Mark S 2
·
1⤊
0⤋
the dentists dont use novacaine for a children till 14
2007-01-03 13:49:59
·
answer #7
·
answered by Alina S 1
·
0⤊
1⤋
So funny you mentioned this! I just got a fill the other day and my doctor started drilling with no pain medication!!!! The last time I had a fill, I was super young so I said, "What are you doing?!?!" She said, "Did you want pain medication? You don't need it...it's not a deep one..." I said, "Give me a shot now!"
2007-01-03 13:47:02
·
answer #8
·
answered by Anonymous
·
0⤊
0⤋