Isotretinoin (Roaccutane) is a form of Vitamin A that is prescribed by dermatologists (skin specialists) for severe acne that has not improved with other milder therapy. It is especially recommended if cysts are present and when the body (e.g. chest and back) is affected rather than only the face.
Isotretinoin makes the sebaceous glands less productive, reduces the size of the sebaceous glands and reduces the inflammation (redness and swelling) of the skin in acne. It affects the development of pimples and blackheads and reduces the amount of the bacteria "Propionibacterium acnes". Isotretinoin must not be used in people with a bad liver or kidneys, people with very high blood lipids or allergy to isotretinoin or other ingredients of the capsule. It is extremely important that women taking isotretinoin do not become pregnant while on isotretinoin or for 1 month after stopping the medicine. Isotretinoin is teratogenic, which means that it is extremely damaging to an unborn child. Special care is required if patients have a history of depression as there have been reports of depression and other similar problems in patients on isotretinoin, although it has not be confirmed if isotretinoin was the cause. The manufacturers recommend that liver function and lipids should be checked prior to starting treatment, one month after the start of treatment and in the case of lipids, after the treatment has finished, and in the case of liver function, every three months. Overweight people, diabetics or people with alcoholism or lipid metabolism disorders will need to have blood tests more often. The side effects of isotretinoin are generally those of too much vitamin A. Many patients will have dry: Skin, lips, inside the nose, eyes, mouth, throat (can temporarily affect the voice) , some other possible side effects are: Itchy skin, nail problems, hair thinning or loss, increased sensitivity to sunlight. Muscle and joint pain (quite common), headache, changes in blood tests e.g. liver tests, cholesterol. Infections including skin infections. There are a number of other side effects that can occur, so check with your doctor or pharmacist if you think you may have a side effect of the medicine.
Hope this helps
Matador 89
2007-01-03 09:29:11
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answer #1
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answered by Anonymous
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There is a lot of information. Please refer to this website.
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a681043.html#why
2007-01-03 08:58:49
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answer #2
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answered by kallmetigger 4
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