I want in formation on cerebellum malaria & its effects?

Question

what happen when it take place & pls send the picture of it were it take place in brain? Did feet & all this thing take place? Pls friend it is uregent to know me about this?

Answer 1

The major feature of cerebral malaria is the existence of cytoadherence of parasitized erythrocytes to the endothelium of cerebral capillaries and venules, resulting in the sequestration and tight packing of infected cells in these vessels. The meninges are grossly congested, the smaller vessels being packed with parasitized cells.

• The brain itself may show gross congestion only, but it is usually leaden or "slate-grey" in colour, as a result of the smaller vessels of the grey matter being packed with red cells containing pigmented parasites in all stages of development. Gross congestion of the vessels is invariable, and in the majority of instances numerous petechial haemorrhages are evident in the white matter of the cerebrum, brain stem and cerebellum; ring haemorrhages are a striking feature. These consist of a central "blocked" vessel (most frequently an arteriole), containing an agglutinated mass of parasitized erythrocytes surrounded by brain tissue, and then by a ring of extravasated red blood cells.

• Death can occur in cerebral malaria with few parasites in the majority of the cerebral vessels (particularly when considering that death may occur after the patient has been several days in coma and under antimalarial treatment).

Answer 2

Cerebellum Malaria is probably the most dangerous kind of Malaria. But no worries, it can be treated...the infected person must immediately go to the hospital and stay there a couple of days to be monitored. Though it can be fatal, the treatment is quite standard and as long as you go to the hospital you will be fine. Symptoms are typical Malaria symptoms, it is the blood test that narrows it down to what kind of malaria it is. A very high fever, throwing up, and constant chills are signs that you might be infected with Malaria. Safest thing to do is to get a blood test at a clinic to find out whether you have just a fever/flu or if it is malaria. I lived in Ivory Coast for 3 years, and caught Malaria twice...a couple of my friends had Cerebellum Malaria, but all were fine after 3 days in the hospital. If it makes you feel better, Malaria is known for being a dangerously fatal disease because it is widespread throughout Africa and many people cannot afford the treatment. If treated, the risk of fatality is below 5%. For Cerebellum Malaria, if you do not get treated the first couple of days, you can risk brain damage.

Answer 3

Central nervous system manifestations are well known and are more dangerous. The commoner being cerebral malaria while the cerebellar manifestations are rare, but if they are diagnosed early they are treatable. The various cerebellar manifestations in malaria may be confused with viral encephalitis, however the presence of short typical fever with positive malarial parasite suggest the diagnosis and if treated early and properly may recover completely. Other possible cause may be high grade fever which could alone produce cerebellar manifestation2. In malaria there is extensive injury to Purkinje's cells of cerebellum but this is non specific. Ringdon et al have described cerebellar manifestation in malaria3.

Answer 4

http://www.impact-malaria.com/FR/EPS/Formations_et_cours_internationaux/Formation_de_la_Liverpool_School_LSTMH/cours_liverpool/Unit_3/3_5_2.html