Is there any know disease that prevents hypertrophy?

Question

Within bodybuilding realms, hypertrophy is the growth/addition of muscle mass. I'm trying to determine if there is any known disease that actually works against the normal biomechanical, biochemical, and biophysical properties associated with hypertrophy when one is following the same diet and exercise regime used by bodybuilders and professional athletes to add muscle mass?

We all know that genetics plays a factor in body shape and hype. But is there a known genetic component/factor that actually prevents hypertrophy?

In asking this question I'm not talking about diseases such as muscular dystrophy, cancer, or any wasting syndromes which prevent one from exercising in the first place. I'm talking about a person who appears to be basically healthy and is able to participate in regular exercise (bodybuilding routines) and yet because of some underlying genetic or biochemical defect is unable to realize hypertrophy.

Thanks in advance for all comments!

Answer 1

Prevention

The best way to help prevent left ventricular hypertrophy is to keep your blood pressure within the limits recommended by your doctor. Here are a few tips to better manage your blood pressure:

* Monitor high blood pressure. If you have high blood pressure, get a home blood pressure measuring device and check your blood pressure frequently. Schedule regular checkups with your doctor.
* Make time for exercise. Regular exercise helps to lower blood pressure. Aim to engage in 30 minutes of moderate activity at least five times a week. Talk to your doctor about whether you need to restrict certain physical activities, such as weightlifting, which may temporarily raise your blood pressure.
* Watch your diet. Eat foods high in fat and salt sparingly and increase your consumption of vegetables, fruits and low-fat dairy products. Drink alcohol and caffeinated beverages in moderation.

In addition to controlling high blood pressure, it's important to monitor other health conditions that increase your risk of heart disease, including diabetes and high blood cholesterol.
http://www.mayoclinic.com/health/left-ventricular-hypertrophy/DS00680/DSECTION=9