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2006-12-15 05:08:15 · 6 answers · asked by HEATHER B 1 in Health Diseases & Conditions Other - Diseases

6 answers

The site below is a good one..;

2006-12-15 08:32:01 · answer #1 · answered by huggz 7 · 2 0

Huntingtons Chorea...know known as Huntington's disease is pretty nasty and incurable.

It is heredity and usually doesn't miss a generation. No one knows why is manifests or what causes it...as there are a lot of cases where no previous family members have been known to have it.

I've nurses a lot of people with Huntington's as generally they are placed in Psychiatric hospitals.

Usually first signs of the disease occur around the age of 25 - 40yrs. It tends to progress to death over the next 15-20 years.

Huntington's Chorea is a genetic disease associated with characteristic jerky involuntary spasms, called chorea. The symptoms are as follows:
Abnormal movements, Intellectual changes, Behavioral changes,
Irritability, Antisocial behaviour, Moodiness, Psychiatric disorders

Later:

Dementia (senility), Chorea -- repetitively purposeless movements of the extremities, Rigidity may occur

There are loads of sites on line that will give you all the information you require.

www.ninds.nih.gov/disorders/huntington/huntington.htm

2006-12-15 13:23:43 · answer #2 · answered by audrey_o 5 · 0 0

Huntington's is an inherited disease that is both progressive and degenerative, affecting cognition, emotion, and movement. The window of diagnosis is between the age of 30-40, but as with any disease, can occur much earlier or later in life. For this there is no cure and treatment focuses on preventing complications. There are medications available to treat the psychological symptoms that result as well.

2006-12-15 13:22:00 · answer #3 · answered by femmefacetious 1 · 0 0

Huntington disease (HD), also known as Huntington chorea (HC), is an inherited disease characterized by choreiform movements (the adjective used to describe involuntary movement where there are jerky displacements of short duration affecting the limbs and the face) and progressive dementia. In adults, HD most often causes involuntary movements, but rigidity can also be a feature of the disease. The initial diagnosis is rarely established in the emergency department, but patients with established disease may present there because of worsening symptoms. Another way of describing it is that it is an inherited neurodegeneration that often occurs in the fourth or fifth generation of life. In the gene that controls Huntington disease, there is a series of CAG repeats. When that number of repeats is too large, it results in the synthesis of a protein that has an odd shape because a section of it is expanded. As a result, the abnormal protein causes the deterioration in neurological function that is associated with Huntington disease. As the size of the repeat section increases over generations, the age of onset of the disease becomes earlier.
Pathophysiology,- HD is inherited as an autosomal dominant disorder with complete penetrance. [The inheritance of genetic diseases, abnormalities, or traits is described by both the type of chromosome on which the abnormal gene resides (autosomal or sex chromosome), and by whether the trait itself is dominant or recessive. This is due to whether a single defective gene from one parent (dominant inheritance) or both copies of the gene (one from each parent) are defective (recessive inheritance). ] An HD gene has been identified with an abnormal protein product (huntingtin) that can be identified in the brain. The link between this protein and the selective loss of neuronal groups in the CNS remains to be established. HD has now been identified genetically as a trinucleotide CAG-repeat mutation on chromosome 4. The CAG repeat length may be important in determining the age of onset and the rate of disease progression.

Hope this helps
Matador 89

2006-12-15 13:44:30 · answer #4 · answered by Anonymous · 0 0

This is one of the nastier hereditary diseases.

Here is a link to the Huntington's Disease Association. It gives you lots of information on causes, diagnosis, treatment and care:

http://www.hda.org.uk/

2006-12-15 13:15:06 · answer #5 · answered by mcfifi 6 · 0 0

Woody Guthrie disease

2006-12-15 13:29:59 · answer #6 · answered by Perseus 3 · 0 0

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