what is andersons-fabry's disease?

Answer 1

In plain terms is where fats in your cells attach themselves to your internal organs or vessels which causes problems once the accumulated levels are too high. Can cause blotches, lesions and even organ failure.

Answer 2

A sex-linked disorder of glycolipid metabolism characterized by a variety of progressive symptoms including fevers, hypertension, and purple skin lesions, with death resulting from renal, cardiac, or cerebrovascular complications. Also called angiokeratoma corporis diffusum.

Also known as:
Anderson’s syndrome
Anderson-Fabry syndrome
Fabry’s syndrome
Fabry-Anderson disease
Morbus Anderson-Fabry
Ruiter-Pompen syndrome
Ruiter-Pompen-Wyers syndrome
Sweeley-Klionsky disease or syndrome

Associated persons:
William Anderson
Johannes Fabry
Bernard L. Klionsky
Arnold Willem Maria Pompen
Maximillian Ruiter
Charles C. Sweeley
Herman Joseph Gerard Wyers

Description:
A rare, inherited metabolic disease in which a glycolipid, ceramide trihexoside, accumulates in blood vessels, as well as in numerous tissues and organs. The excessive amounts present in the kidneys and other organs impairs their function. Due to absence of æ-galactosyl hydrolase. Patients present with the skin lesions, small red spots seen on the lower abdomen, thighs and scrotum, corneal opacities, episodes of fever, primary aparasthesia of the extremities and peripheral oedema and renal failure. Prevalent in males, who present full-blown syndrome, females may present a partial form. Symptoms start in childhood or at puberty. Death usually occurs in adulthood. Family history. An X-linked syndrome with complete penetrance and variable clinical expressivity in males. Female carrier asymptomatic.

The disturbance was first described in 1898 by Fabry in Germany and Anderson in England. Anderson's patient was a male aged 39 years who had an eruption on his trunk, genitals and proximal limbs. He recorded that the patient had been afflicted since childhood and that varicose veins, rectal bleeding and albuminuria had developed. Anderson termed the condition "angiokeratoma" and suggested that there might be generalised changes in the vascular system. Fabry conducted independent studies of an affected boy. In his article Fabry used the designation "purpura haemorrhagica nodularis". A further case was recognised in Egypt by Frank Cole Madden (1873-1929) in 1912 and the condition was mentioned again by Fabry in 1915 under the title "Angiokeratoma corporis naeviforme". Fabry retained his interest in the disorder and published the autopsy findings after his patient's death in 1930.

Answer 3

A rare disease that requires special expensive IV medications one a month for the person who has it to live. It has something to do with the blood, I think a guy in our city has it.

Answer 4

1

Answer 5

http://www.wrongdiagnosis.com/medical/anderson_fabry_disease.htm