dry antibiotic reconstituted ..... ?

Question

A dry antibiotic is reconstituted with 128ml of water to yield 250mg/5ml. If the child weighs 66 pounds what will the dose be at 5mg/kg/dose? If the medication is given qid x 10 days, will the 150ml bottle be enough?

Answer 1

You have 150 ml of antibiotic solution. The concentration is 250mg/5ml.

The weight of child is 66 pounds = 30Kg.

Now calculate the amnt. of antibiotic needed for ONE dose.
ie. 5mg/ Kg
So for 30Kg - 5mg X 30 = 150mg.

Then find out the volume of the drug needed (ie.150mg).

250mg/5 ml
50mg/ ml
150 mg/ 3ml

So you need 3 ml of the drug for each dose.

Then calculate the number of doses needed:
qid = 4 times a day & You need this for 10 days.
So total doses needed - 4X10 = 40

Now calculate the total volume needed for 10days.
no. of doses X the volume for each dose. 40X3= 120.

Since you have 150 ml this is enough for 10days if given qid.

Answer 2

250mg/5ml = 50 mg/ml

66 lbs x 0.454= 30 kg
5mg/kg/dose= 5 x 30
or, 150 mg per dose

QID= four times daily

4 dose/day= 600mg day
150 ml of 50mg/ml solution is 7500 mg
so, 600mg/day for 10 days = 6000mg total needed
since you have 7500mg the kid gets to live.