I take a low dose of inderal and I'm wondering if I can take one benadryl that only has one ingredient (diphenhydramine)....will there be any bad side affects besides drowsiness??? I can't get through to my pharmacist tonight for some reason...
2006-12-08 18:16:29 · 5 answers · asked by hwall 4 in Health ➔ Other - Health
From AccessMedNet ( http://www.accessmednet.com/prescription-drug-information/inderal_propranolol.html#interactions ):
Inderal Interactions
Some medications may interact with Inderal (propranolol) treatment, and may require either careful monitoring or the selection of a different treatment if their use is necessary. Certain over the counter treatments may result in interactions as well. Serious circulatory side effects could result fram drug interactions with this medicine.
Only your doctor can decide if it's safe for you to mix other medication with prescription treatments, but be especially sure to inform them if you use any of the following:
Alcohol - Use of alcohol while being treated with Inderal may lead to low blood pressure or oversedation.
Aldomet (methyldopa) - Risk of blood pressure increase with increased stress.
Allergy medication or skin test agents - Propranolol may greatly increase the likelihood of a serious allergic reaction.
Anesthetics like lidocaine may have their effects dangerously increased. Inform your doctor or dentist that you take Inderal before having any surgery.
Antacids may decrease propranolol's effectiveness.
Anti-diabetic drugs or Insulin - This combination may result in undesirably low blood sugar, regular testing for hypoglycemia is recommended.
Anti-hypertensive drugs of any other type may result in undesirably low blood pressure. Reduced dosages could be necessary.
Auralgan (antipyrine)
Bronchodilators of the xanthine (thioxanthine) class (Aminophylline, Dyphylline, Oxtriphylline, Somophyllin, Theo-Dur, etc...) - May be less effective asthma treatments when combined with propranolol.
Caffeine (excess coffee or cola, No-Doz, Vivarin) - The effects of both caffeine and propranolol may cancel each other out.
Calcium channel blockers - Medications like Bepadin (bepridil), Calan (verapamil), Cardene (nicardipine), Cardizem (diltiazem), DynaCirc (isradipine), Norvasc (amlodipine), Nimotop (nimodipine), Plendil (felodipine), Procardia (nifedipine), or Sibelium (flunarizine) may cause unwanted heart problems when combined with beta-blockers like propranolol.
Catapres (clonidine) - Neither medication should be stopped abruptly if used together, increased risk of sudden high blood pressure.
Cipro (ciprofloxacin) - Can cause propranolol buildup.
Colestid (colestipol) - Treatment benefits may be decreased.
Cordarone (amiodarone) - Do not combine, abnormal hearth rhythms or low pulse may result.
Coumadin (warfarin) - Increased risk of bleeding, dosage adjustment may be needed.
Diuretics may increase propranolols effects, as well as the risk of side effects.
Epinephrine/Adrenalin - Increased blood pressure and slower heart rate may result.
Ergotamine based migraine treatments such as DHE 45 injections, Cafergot, Ergostat, Migranal nasal spray, or Sansert, can cause blood vessel constriction or decreased blood flow to the extremities in combination with propranolol.
Ginseng - May increase blood pressure.
Goldenseal - May increase blood pressure.
Hawthorn - May increase blood pressure.
Indian Snakeroot - This herb is approved in Germany as an anti-hypertensive treatment. Consult your doctor if you wish to combine therapies, as there may be some risk of undesirably low blood pressure when two anti-hypertensive treatments are used together.
Lanoxin (digoxin) - May result in undesirably slow heartbeat.
Licorice - May increase blood pressure unless deglycyrrhizinated. Glycyrrhizin is a compound in licorice which seems to produce higher blood pressure. The majority of licorice flavored candies do not contain enough of the herb to make a difference, but herbal teas containing it should be avoided.
Ma Huang - May increase blood pressure.
MAO inhibitors - Inderal must never be mixed with MAO (monoamine oxidase) inhibitors, a class of antidepressants and antisenility drugs, such as Eldepryl (selegiline), Furoxone (furazolidone), Nardil (phenelzine), Marplan (isocarboxazid), or Parnate (tranylcypromine). Never use Inderal within 2 weeks of starting or stopping an MAO inhibitor. Patients over 65 should allow a longer wait period between using Inderal and an MAO, as MAOs may stay in their system longer than in other patients. Dangerously high blood pressure could result from this combination.
Migraine medications of the triptan class such as Amerge (naratriptan), Imitrex (sumatriptan), Maxalt (rizatriptan), or Zomig (zolmitriptan) can increase the risk of side effects from either drug when used with propranolol. Speak to your doctor about the risks involved in your specific case, as some individuals have used them together safely.
Nicotine can decrease the effectiveness of Inderal directly by speeding its elimination from the body, and indirectly by promoting high blood pressure and other cardiovascular problems. No current treatment for cardiovascular conditions can entirely cancel the negative effects of nicotine use on the circulatory system.
Nipolept (zotepine) - These two treatments increase each other's potential toxicity.
Non-steroidal anti-inflammatories (NSAIDs) such as Butazolidine (phenylbutazone), Clinoril (sulindac), Ibuprofen (Motrin), Indocin (indomethacin), Feldene (piroxicam), Naprosyn (naproxen), Toradol (ketorolac), and others, as well as combination pain killers which contain NSAIDs, may reduce the medication's effectiveness in reducing high blood pressure.
Norpace (disopyramide) - Undesirable propranolol buildup may occur.
Propacil (propylthiouracil) - May increase propranolol's effects.
Propoxyphene - Can lead to medication buildup.
Protease inhibitors such as Agenerase (amprenavir), Norvir (ritonavir), and perhaps others, may lead to higher levels of propranolol in the body.
Proventil (albuterol) - May be less effective when combined with propranolol.
Provigil (modafinil) - Dosage adjustments may be necessary.
Quinaglute (quinidine) - Increases risk of heart failure, low blood pressure, or slow heart rate. If medications are to be used together, careful monitoring is advised. May increase the risk of adverse Inderal side effects.
Reglan (metoclopramide) - Can increase the effects of immediate release forms of this treatment.
Reserpine - This combination may cause central nervous system or cardiovascular depression.
Rifampin (Rifadin, Rimactane) - May decrease usefulness of propranolol.
Rythmol (propafenone) - These combined treatments may cause drug build up in the body, esp. with Rythmol doses higher than 150 mg daily.
Saw Palmetto - May increase blood pressure.
Sedatives like Fioricet (butalbital, acetaminophen, and caffeine), Fiorinal, Phenobarbitol, Seconal, or other barbiturates may decrease the effectiveness of your treatment.
Selective serotonin reuptake inhibitors (SSRIs) like Celexa (citalopram), Paxil (paroxetine), Prozac (fluoxetine), Luvox (fluvoxamine), or Zoloft (sertraline) may cause side effects like slow heartbeat, sedation, chest pain, or a toxic buildup of propranolol.
Serzone (nefazodone) - This combination can decrease the usefulness of propranolol and increase the risk of a toxic buildup of Serzone.
Street Drugs - Cocaine may lead to a heart attack if taken with this medication. Individuals taking prescription treatments are strongly advised to avoid all street drugs, as the possible interactions could be dangerous or life threatening.
Tagamet (cimetidine) - May cause drug buildup in the body.
Tapazole (methimazole) - Dosage adjustments may be needed.
Thorazine (chlorpromazine) - Effects of propranolol may be increased.
Wytensin (guanabenz) - Neither medication should be stopped abruptly if used together, there's increased risk of sudden high blood pressure.
Yohimbe - May increase blood pressure.
Zocor (simvastatin) - May decrease blood levels of propranolol.
Zyflo (zileuton)
From MedicineNet.com ( http://www.medicinenet.com/diphenhydramine/article.htm ):
DRUG INTERACTIONS: Diphenhydramine adds to (exaggerates) the sedating effects of alcohol and other drugs than can cause sedation such as the benzodiazepine class of anti-anxiety drugs (e.g., Valium, Ativan, Klonopin, Xanax), the narcotic class of pain medications and its derivatives (e.g., Percocet, Vicodin, Dilaudid, Codeine, Darvon), the tricyclic class of antidepressants (e.g., Elavil, Tofranil, Norpramin), and certain antihypertensive medications (e.g., Catapres, Inderal). Diphenhydramine can also intensify the drying effects of other medications with anticholinergic properties (e.g., Bentyl, Urecholine, Probanthine).
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2006-12-09 08:23:42 · answer #1 · answered by funnyrob01 4 · 2⤊ 0⤋
Diphenhydramine Drug Interactions
2016-12-30 11:19:27 · answer #2 · answered by scharfschwerdt 3 · 0⤊ 0⤋
This Site Might Help You.
RE:
Any drug interaction with Inderal and Diphenhydramine?
I take a low dose of inderal and I'm wondering if I can take one benadryl that only has one ingredient (diphenhydramine)....will there be any bad side affects besides drowsiness??? I can't get through to my pharmacist tonight for some reason...
2015-08-24 01:49:59 · answer #3 · answered by ? 1 · 0⤊ 0⤋
You are (already) overdosing. You shouldn't take more than 1 kind of antihistamine, they all do the same thing. Taking 2 of X and 2 of Y is the same as taking 4 of X. You can take an antihistamine and decongestant at the same time, and even a pain relieving tablet, but not 2 anti-histamines, unless a doctor is monitoring your situation. You're asking for trouble, your poor liver. I hope you don't drink alcohol too. Look for antihistamines that people complain cause drowsiness, unfortunately these are the most effective, but you would have to put up with the drowsiness in exchange for better relief.
2016-03-18 21:42:02 · answer #4 · answered by Anonymous · 0⤊ 0⤋
don't take your drug advice from anonymous people with dubious qualification to answer. Are there no 24 hour pharmacies where you live?
btw aside from the drowsiness, they are OK to take together. That's what you pharmacist told you......right?
2006-12-10 04:09:40 · answer #5 · answered by jloertscher 5 · 0⤊ 0⤋