What is administered to a patient in case of Warferin overdosage?

Question

only reply if your answer is from a tustworthy source. thank you

Answer 1

Life threatening haemorrhage:

immediate 5 mg vitamin K by slow intravenous injection; also a concentrate of factor II, IX, X, with factor VII concentrate (if available)

Less severe haemorrhage, such as epistaxis:

withold warfarin for one or more days
consider administering vitamin K 0.5-2.0 mg i.v.

INR greater than 4.5 without haemorrhage:

withdraw warfarin therapy for one or two days and then review; an alternative is to give oral vitamin K - there is evidence that in patients receiving warfarin and who had an INR between 4.5 and 10.0, low dose vitamin K lowered the INR to between 1.8 and 3.2 the day after administration (2)

Answer 2

1

Answer 3

First you administer activated charcoal (which is available over the counter at places like Walgreens) to try and "soak up" as much of it as possible. Sometimes gastric emptying is done. Vitamin K should only be given if it's a small amount that was overdosed, if it's a large amount, Vitamin K only masks other symptoms, and can hide the onset of anticoagulant effects. Small dose overdose, Vitamin K is appropriate only after anticoagulation develops. The higher the overdose, the more serious the side effects, and in any case, small or large overdose, the person who overdosed should see a doctor.

Answer 4

warfarin overdose


Seek expert advice.

Life threatening haemorrhage:

immediate 5 mg vitamin K by slow intravenous injection; also a concentrate of factor II, IX, X, with factor VII concentrate (if available)
Less severe haemorrhage, such as epistaxis:

withold warfarin for one or more days
consider administering vitamin K 0.5-2.0 mg i.v.
INR greater than 4.5 without haemorrhage:

withdraw warfarin therapy for one or two days and then review; an alternative is to give oral vitamin K - there is evidence that in patients receiving warfarin and who had an INR between 4.5 and 10.0, low dose vitamin K lowered the INR to between 1.8 and 3.2 the day after administration (2)
Unexpected bleeding at therapeutic levels:

investigate for possible cause e.g. alimentary or renal disease

Answer 5

Are you referring to warfarin aka Coumadin as in an anticoagulant or as a rat poison? Wikipedia has an excellent article on the subject of warfarin.
If you are referring to a rodentcide or the super warfarin, Brodifacoum, then a more life threatening condition exists.
See the CDC.gov sites below for the authoritive advise for both chemicals. They even list a NIOSH for warfarin. Please note that regardless of the various spellings this chemical is a teratogen and must never be taken by pregnant women.
Warfarin can be reversed with vitamin K, or for rapid reversal (e.g. in case of severe bleeding), with fresh frozen plasma but this treatment is being replaced by use of prothrombin complex concentrate. Warfarin is one of the most common drugs associated with medication errors, see CDC death reports below.

Answer 6

Symptoms of a warfarin overdose may include bruising; small, broken blood vessels under the skin; excessive bleeding from cuts or wounds; bleeding from the gums; blood in the stools, urine, or vomit; and heavy menstrual periods in women.

Medical attention should be sought immediately if anyone has used more than the dose prescribed.

Answer 7

immediate 5 mg vitamin K by slow intravenous injection; also a concentrate of factor II, IX, X, with factor VII concentrate

Answer 8

Vitamin K, or for procedures Fresh frozen plasma for short term reduction of PT/INR.

Answer 9

Vitamin K.

Answer 10

Look it up - don't come on here asking for "trustworthy source". You want to know the right answer then do your own homework. Lazy sod.