could a 5 lb fishing line be made with with special custom made pulleys ,diffrent ratios, lift 100 lb?

Question

or its just equal to all pulley drag no diffrence about 5 lb

Answer 1

Of course.
You would only need to arrange the double, compound pulley system to give you a minimum 20:1 mechanical advantage.
Unfortunately, you would be pulling 20 feet of line to lift the hundred pounds 1 foot.

Answer 2

Yes, but only if the connection between the load and a pulley could also support 100 pounds. This could be many lengths of 5 pound fishing line in parallel

Answer 3

if you double the fishing line back and forth between two "blocks" (a bank of pulleys) you could lift 100 pounds with 5 pound line.

you would have to double 10 times back and forth; you need 20 strands of 5 lb line acting in parallel to lift your 100 lbs.