My mother has it, she's had it for 11 years now and I still don't know what causes it!
2006-12-04 06:19:38 · 10 answers · asked by Pope Barley 4 in Health ➔ Diseases & Conditions ➔ Other - Diseases
Oh, and I'm not taking about the sort of arthirits you get in your back after bending over etc. that's Oesteo arthiritis.
2006-12-04 06:20:47 · update #1
BtRix, I know it's not genetic, or she would have had it from birth and I would have it
2006-12-04 06:22:54 · update #2
It has long been suspected that RA is infectious. It could be due to food allergies or external organisms. An offending organism causes an immune response that leaves behind antibodies that are specific to that organism.
They begin an immune attack against, in this case, the synovium, because some molecule in the synovium "looks like" a molecule on the offending organism that created the initial immune reaction - this phenomenon is called molecular mimicry.
But physical and emotional effects, stress and improper diet also play a role in the disease.
Autoimmune diseases require that the affected individual have a genetic defect in the ability to distinguish self from foreign molecules. There are markers on many cells that confer this self-identifying feature.
90% of patients with RA have the cluster of markers known as the HLA-DR4/DR1 cluster, whereas only 40% of unaffected controls do. Thus, in theory, RA requires susceptibility to the disease through genetic endowment with specific markers and an infectious event that triggers an autoimmune response.
Once triggered, the immune response causes inflammation of the synovium.
2006-12-04 06:27:27 · answer #1 · answered by thinkbeinteresting 2 · 0⤊ 0⤋
It is genetic to an extent and no she wouldn't have had it from birth, I have lupus with is in the same class of disease and I didn't 'have' it till I was 20something. So yes it is genetic and environmental. At some point she prolly got sick, nothing serious just had some sort of immune response and it cause her immune system to work harder, then her immune system got confused and started attacking her own body. Most of the pain from RA is cause by the bodies inflammatory response in the synovial (sp) fluid around the joints, which puts pressure on the joint and causes them to erode.
2006-12-04 14:44:54 · answer #2 · answered by Dizzy 2 · 0⤊ 0⤋
I was doing autopsies at the Minnesota .....well let's say for a museum with some other influential doctors and heads of schools all heads in their respective fields. I found out some Egyptian mummies that were as old as four thousand years had severe signs of Arthritis and Rheumatism and, various forms of it. It also shows up on bones of prehistoric cro-magnon so, I guess it's been with us for awhile and, it's not a fully accredited scientific belief but we can toss it around. It's been suggested that it's been with man as an aging agent and will always be with us.
2006-12-04 16:22:18 · answer #3 · answered by cowboydoc 7 · 0⤊ 0⤋
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2006-12-04 14:27:11 · answer #4 · answered by Mark G 1 · 0⤊ 0⤋
Rheumatoid arthritis (RA) is traditionally considered a chronic, inflammatory autoimmune disorder that causes the immune system to attack the joints. It is a disabling and painful inflammatory condition, which can lead to substantial loss of mobility due to pain and joint destruction. RA is a systemic disease, often affecting extra-articular tissues throughout the body including the skin, blood vessels, heart, lungs, and muscles.
2006-12-04 14:22:49 · answer #5 · answered by eeaglenest 3 · 0⤊ 0⤋
It is a disease of the auto immune system. They are diseases that cause the body to attact itself, in the case of rheumatoid arthritis it is the joints of the body it attacks. The cause is unknown, why would the body create diseases that makes the body attack itself?
2006-12-04 14:23:28 · answer #6 · answered by smartypants909 7 · 0⤊ 0⤋
I believe this is in the category of auto-immune diseases like Lupus and other types. I would check under that category, several things can cause this, stress, a virus, etc etc
2006-12-04 14:21:27 · answer #7 · answered by chumbawumba91501 3 · 1⤊ 0⤋
The cause of rheumatoid arthritis is unknown. Even though infectious agents such as viruses, bacteria, and fungi have long been suspected, none has been proven as the cause.
2006-12-04 14:21:55 · answer #8 · answered by S H 6 · 0⤊ 0⤋
It's genetic. It can't be cured or prevented.
2006-12-04 14:20:44 · answer #9 · answered by Anonymous · 0⤊ 1⤋
it's autoimmune. it's like your antibodies attacks your own system.
2006-12-05 02:59:56 · answer #10 · answered by haru 2 · 0⤊ 0⤋