Is sanflippo Syndrome a genetic disorder?

Question

If so, where can i find a karyotype of it?? And where is the problem found?

Answer 1

Sanfilippo syndrome, or Mucopolysaccharidosis III (MPS-III) is a rare genetic disease.

Genetics of MPS-III MPS-III
type enzyme gene location
MPS-III A heparan N-sulfatase 17q25.3
MPS-III B N-acetyl-alpha-D-glucosaminidase 17q21
MPS-III C acetyl-CoA:alpha-glucosaminide acetyltransferase 8p11-q13
MPS-III D N-acetylglucosamine-G-sulfate sulfatase 12q14

it affects the breakdown of heparan sulfate

Answer 2

Sanfilippo syndrome as stated is an autosomal recessive disease which is part of the mucopolysaccharide storage disease. The problem is these enzymes are found intracellular and help breakdown extracellular substance as previously mentioned above.