dangers of coke[drug]..?

Question

what are some of the dangers of coccaine? what are the immediate effects, and the long term effects? what about if you only ues it ONCE? [i am NOT gunna do it, a friend is. i wanna stop her from it ]

Answer 1

addiction is one negative, heart attack is another. Without going to those extremes diarrhea, runny nose, vomiting, uncontrollable shaking, sweating, dehydration. and being a general jerk to everyone you know

Oh yea you have to pay to feel this great

sounds like fun!

Answer 2

Cocaine is VERY addictive. The best thing you can do for your life is to never try it even once, or any other drug. A person can become addicted the very first time they try it. Before you know it you wont care about anything but getting your drug. This includes lying and stealing from anyone you know and love, you completely ruin your body, your teeth, skin, bones, heart everything. You will look like death walking down the street. And then one day when you do it long enough you WILL DIE. Thats if your lucky and dont die the first time you do it, which can happen. Read the article below. I really hope you or your friend choose not to make such a bad decision and dont try this drug.

Answer 3

Cocaine can cause a very strong psychological addiction.

Nasal use, due to its ability to constrict blood flow, promotes ulcers in the nasal septum which can carry staph bacteria directly into the brain.

Injection can cause vasospasm that can shut blood supply to a hand or other extremity, resulting in amputation.

Stimulation of the heart can result in a rise in blood pressure to cause a stroke (busted blood vessel in brain), or a fatal arrhythmia.

Long term effects can be economic and other personal losses, including criminal history. Sometimes users sell drugs to sustain their habit, but this type of criminal history precludes student loans for higher education.

Answer 4

Immediate dangers of benzoylmethyl ecgonine (cocaine hydrochloride), i suspect your speaking of, aren't as bad as people are making them out to be. Dangers increase with route of admin., worst being I.V. injection, second being smoked freebase substance, third being insufflation, and lastly orally, which shows the lowest potential for addiction. The LD50 of cocaine hydrochloride stands as 95.1 mg/kg I.V. This means that unless your friend who perhaps weighs around 150?, would have to inject about 6 grams to potentially kill themselves. This is to say PURE substance. It is 100% gaurenteed that your friend will not be using pure substance, but infact a heavyly aldulterated one. People who sell expensive drugs like cocaine regularly "cut" and "adulterate" their cocaine to increase overall weight, thus increasing profit. Common adulterants include, amphetamines, caffeine, lidocaine, talcum powder. Your friend has more of a chance of encountering danger do to the fact that (s)he will be also ingesting an unknown adulterant, rather than the cocaine itself. If your friend tries it, dont freak. Everyone tries some type of pyschoactive (mind altering drug), at some point in time in their lives. My only advice is DO NOT let them develop a habit of it.

Answer 5

Meth customers are ordinary for going into suits of rages. Is he up for days? Does he sleep so deep it rather is annoying to wake him? Does he have sore on his physique? (face or hands) The rages in many instances start up whilst the guy is coming down off of the severe.

Answer 6

Even using coke just once can cause addiction and that is immediate.

Answer 7

Effects and health issues

Acute
Cocaine is a potent central nervous system stimulant. Its effects can last from 20 minutes to several hours, depending upon the dosage of cocaine taken, purity, and method of administration.

The initial signs of stimulation are hyperactivity, restlessness, increased blood pressure, increased heart rate and euphoria. The euphoria is sometimes followed by feelings of discomfort and depression and a craving to experience the drug again. Sexual interest and pleasure can be amplified. Side effects can include twitching, paranoia, and impotence, which usually increases with frequent usage.

With excessive dosage the drug can produce hallucinations, paranoid delusions, tachycardia, itching, and formication.

Overdose causes tachyarrhythmias and a marked elevation of blood pressure. These can be life-threatening, especially if the user has existing cardiac problems.

The LD50 of cocaine when administered to mice is 95.1 mg/kg.Toxicity results in seizures, followed by respiratory and circulatory depression of medullar origin. This may lead to death from respiratory failure, stroke, cerebral hemorrhage, or heart-failure. Cocaine is also highly pyrogenic, because the stimulation and increased muscular activity cause greater heat production. Heat loss is inhibited by the intense vasoconstriction. Cocaine-induced hyperthermia may cause muscle cell destruction and myoglobinuria resulting in renal failure. There is no specific antidote for cocaine overdose.

Cocaine's primary acute effect on brain chemistry is to raise the amount of dopamine and serotonin in the nucleus accumbens (the pleasure center in the brain); this effect ceases, due to metabolism of cocaine to inactive compounds and particularly due to the depletion of the transmitter resources (tachyphylaxis). This can be experienced acutely as feelings of depression, as a "crash" after the initial high. Further mechanisms occur in chronic cocaine use.

Chronic

With chronic cocaine intake, brain cells functionally adapt (respond) to strong imbalances of transmitter levels in order to compensate extremes. So receptors disappear from or reappear on the cell surface, resulting more or less in an "off" or "working mode" respectively, or they change their susceptibility for binding partners (ligands) – mechanisms called down-/upregulation. Chronic cocaine use leads to a DAT upregulation, further contributing to depressed mood states. Finally, a loss of vesicular monoamine transporters, neurofilament proteins, and other morphological changes appear to indicate a long term damage of dopamine neurons.

All these effects contribute to the rise in an abuser's tolerance thus requiring a larger dosage to achieve the same effect. The lack of normal amounts of serotonin and dopamine in the brain is the cause of the dysphoria and depression felt after the initial high. The diagnostic criteria for cocaine withdrawal is characterized by a dysphoric mood, fatigue, unpleasant dreams, insomnia or hypersomnia, E.D., increased appetite, psychomotor retardation or agitation, and anxiety.

Cocaine abuse also has multiple physical health consequences. It is associated with a lifetime risk of heart attack that is seven times that of non-users. During the hour after cocaine is used, heart attack risk rises 24-fold.

Side effects from chronic smoking of cocaine include chest pain, lung trauma, shortness of breath, sore throat, hoarse voice, dyspnea, and an aching, flu-like syndrome. A common misconception is that the smoking of cocaine chemically breaks down tooth enamel and causes tooth decay. However, cocaine does often cause involuntary tooth grinding, known as bruxism, which can deteriorate tooth enamel and lead to gingivitis.

Chronic intranasal usage can degrade the cartilage separating the nostrils (the septum nasi), leading eventually to its complete disappearance. Due to the absorption of the cocaine from cocaine hydrochloride, the remaining hydrochloride forms a dilute hydrochloric acid.

Cocaine may also greatly increase this risk of developing rare autoimmune or connective tissue diseases such as lupus, Goodpasture's disease, vasculitis, glomerulonephritis, Stevens-Johnson syndrome and other diseases.It can also cause a wide array of kidney diseases and renal failure.While these conditions are normally found in chronic use they can also be caused by short term exposure in susceptible individuals.

There have been published studies reporting that cocaine causes changes in the frontal lobe of the brain. The full extent of possible brain deterioration from cocaine use is not known.

That's My Best Medical Answer!

Answer 8

the big danger is DEATH! i know its scary and probably not something you want to tell her, but put it this way. would you rather tell her and shell be mad at you, or not tell her and wait and see what happens with her life. drugs arent worth the risk. if you want your friend to stay safe and healthy tell her this.

Answer 9

well it makes u feel good. if u do to much like 3 grams to yourself u might over does. if u do to much and dont clear your nose afterward u might get a nose bleed. some people grom dependent on it but its all psychological its not physically addictive. its all in the users brain.

Answer 10

it rots your teeth.