2006-11-26 15:27:20 · 5 answers · asked by geniusflightnurse 4 in Science & Mathematics ➔ Medicine
their irregular shape causes them to get stuck in cappilaries and impede circulation.
2006-11-26 15:28:37 · answer #1 · answered by PenguinMoose 3 · 1⤊ 0⤋
Sickled red blood cell (HbS) tend to clump together, making red blood cells sticky, stiff, and more fragile, and causing them to form into a curved, sickle shape. Instead of moving through the bloodstream easily, these sickle cells can clog blood vessels and deprive the body's tissues and organs of the oxygen they need to stay healthy. Sickled cells break down after only about 10 to 20 days while the normal red cells last about 4 months, the reason for causing anemia.âº
2006-11-27 00:13:03 · answer #2 · answered by ♥ lani s 7 · 0⤊ 0⤋
The abnormal shape of sickled rbc and stiffness of rbc membranes makes navigation of the tiny capillaries very difficult causing clogging. Also, the cells lining the inner aspect of blood vessels in sicklers secrets a substance which makes rbc sticky, further worsening the clogging.
2006-11-27 04:47:42 · answer #3 · answered by geebabe 2 · 0⤊ 0⤋
Sickled RBC are clogged together,they have lesser life span and the lysed cells release hemoglobin ,spleen takes up lysed cells to enlarge,and hemoglobin released gets converted into bilirubinto and cause jaundice. All these impair circulation.
2006-11-27 00:48:25 · answer #4 · answered by J.SWAMY I ఇ జ స్వామి 7 · 0⤊ 0⤋
sickle shaped heamoglobin is unable to bind to the oxygen well as compared to the normal haemoglobin...thus the sickle shaped haemoglobin is unable to transport oxygen to the needed parts of body effectively
2006-11-27 07:31:57 · answer #5 · answered by Jaymey 2 · 0⤊ 0⤋