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Why gram-positive sepsis is not as common today as gram-negative sepsis? And why is gram-negative sepsis so dangerous compared to gram-positve sepsis?

2006-11-22 02:15:43 · 3 answers · asked by lovely gem 1 in Health Diseases & Conditions Infectious Diseases

3 answers

gram negative sepsis is more dangerous because of the presence of LPS in the outer membrane of the bacteria, it is not found in gram positive bacteria.

LPS is a very potent antigen and the presence of large amounts of it, especially in the blood stream can lead to a person going into shock.

Many gram negative bacteria can just shed LPS into the environment (blood stream in this case), but you also have to worry about massive lysis of the bacteria doing the same thing. This requires a certain amount of care in administration of the antibiotics so you don't send the patient into shock that way, as well.

I don't agree with the antibiotic comments either. When they talk about antibiotic resistant bacteria becomming a threat, it's stuff like Staph aureus and Enterococcus, both gram positive bacteria. Antibiotic associated diarrhea is caused by Clostridium difficile (most frequently) and C. perfringens (less frequently), both gram positive bacteria.

2006-11-22 06:24:10 · answer #1 · answered by John V 4 · 0 0

Sepsis is a severe systemic an infection. that's not likely which you will possibly grow to be septic via blood transfusion. The screening technique is continually more suitable. With nephrectomy, as with all invasive technique, there is often a threat for an infection even with the undeniable fact that it would likely be community extremely than systemic. And in spite of everything, IV antibiotics could be slightly of postop care. Sepsis occurs with the aid of fact micro organism can enter the blood at any time and be carried from an contaminated organ or portion of the physique to a diverse subsequently infecting different physique areas or organs. Sepsis isn't basically micro organism contained in the blood, that's severe bacterial an infection in the time of the physique.

2016-10-04 06:05:43 · answer #2 · answered by ? 4 · 0 0

Gram positive bacteria are easier to kill with common antibiotics. They can be avoided by using good hygiene practices. Gram negative bacteria produce toxins which can cause breakdown of red blood cells, blood poisoning and shock due to dilatation of small blood vessels.

2006-11-22 04:05:08 · answer #3 · answered by yakkydoc 6 · 0 1

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