How to get to 81st and 2nd ave. in manhattan by train from hoboken?

Answer 1

From Hoboken you have to take the PATH train that goes into Manhattan. It lets you off at 6th Avenue and 33rd Street.

From there you can take the N/R subway to 59th Street. There you transfer to the 6 train and go two stops to 77th Street. That will be on Lexington Avenue.

From 77th & Lexington you just walk East to 2nd Avenue and then four blocks uptown.

Answer 2

after you go thru the tube you take the number 6 train or 5 or 4 to the 77th st stop lets you off on lexington ave you then have to walk north 4 blocks then go east 3 blocks