More Pharmacy Tech math questions.?

Question

If the final volume of vancomycin 2 g vial should reconstituted to a final volume of 20 ml and the instructions indicate to add 13.8 ml of water, what is the powder volume of the vancomycin?

Use the following info for problems 18-20

The Pharmacy stocks penicillin G vials with 5 million units in dry powder form. The reconstitution directions on the vial are as follows.

Desired Concentration Solvent of vial
Units/ml (ml)
250,000 18.2
500,000 8.2
750,000 4.8
1,000,000 3.2

1) What volume of dry powder is contained in this container of penicillin G?

2) If the vial was diluted with 18.2 ml of sterile water, what would the volume needed for 2 million units of penicillin G be?

3) If the vial was diluted with 4.8 ml, what would the volume needed for 3 million units of penicillin G be?

4) If the doctor orders the KCI 40 mEq in 1 L 0.9% NaCl over 8 hr, what is the flow rate in millaliters per hour?

5) The doctor orders 1 g CaCl2 in 250 ml of D5W over 4 hr. How many drops per minute should be administered if the set is calibrated to deliver 40 gtt/ml?

Answer 1

you want me to do your homework for you? I think not.

I worked for about 10 years in a clean room and did this very stuff all day long. So perhaps I can provide some hints.

I will tell you how to do the vancomycin question, and the first Pen G question in hopes that it well help you figure out how to do things.

If the final volume is 20 ml and you are adding 13.8 ml water then the volume of the powder is 20 minus 13.8 ml. The answer is 6.2 ml. I'm not sure where they are getting their vancomycin from, but they got some huge purity issues. Commercially available vancomycin is about 1 gm per ml.


OK you have 5 million units diluted to 250,000 units per ml.

5,000,000/250,000 = 20 ml subtract out 18.2 ml equals 1.8 ml powder volume. Oops, that's the answer to all four question

Now let's see if you can answer what the volume for 2 million units would be.

Answer 2

I don't know about two but I'm confident that you'd only need 500mL or 1:2000 solution to create 1 Litre of a 1:4000. you just dilute it 2:1

Answer 3

I don't think I want to help you pass, or to be able to answer the questions. You might be "somebody I might know" who needs to consult Yahoo answers before he can fill my prescription. There will be lives hanging on your calculations, so I advise you to learn how to do them.